Bus Tickets from Santiago, BR to Florianópolis

Find affordable bus tickets from Santiago, BR to Florianópolis with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Bus Santiago to Florianópolis: Trip Overview

Average Ticket PriceUS$65
Average Bus Trip Duration15h 50m
Number of daily buses1
Earliest bus departure3:00pm
Distance641 km

Santiago to Florianópolis Bus

With Busbud, comparing and booking tickets for a bus from Santiago to Florianópolis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Santiago to Florianópolis will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Santiago to Florianópolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santiago, BR - Florianópolis

  1. How long is the bus ride from Santiago to Florianópolis?

    The trip from Santiago to Florianópolis will take on average 15h 50m. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 15h 50m.

  2. How far is Santiago from Florianópolis?

    Santiago and Florianópolis are 643 km (399 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Santiago to Florianópolis?

    Buses departing from Santiago Onibus in Santiago will take you to Rodoviária de Florianópolis in Florianópolis.

  4. What is the cheapest way to get from Santiago to Florianópolis?

    If you're on a budget, consider traveling by bus to Florianópolis from Santiago; it tends to be more affordable. With a starting ticket price of US$64, this bus becomes your top pick for this journey.

  5. How much does it cost to take the bus from Santiago to Florianópolis?

    The bus from Santiago to Florianópolis will cost you US$65, on average.

  6. Can I take an overnight bus from Santiago to Florianópolis?

    Yes! If you're heading from Santiago to Florianópolis, you'll find buses departing until 3:00pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-03
US$54
06-04
No data
Today
No data
06-06
No data
06-07
No data
06-08
No data
06-09
No data
06-10
No data
busbud logoThe cheapest trip from Santiago to Florianópolis was searched and found on Jun 3, 2025 with a price of US$54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago to Florianópolis, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Santiago to Florianópolis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Santiago to Florianópolis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santiago to Florianópolis that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Santiago to Florianópolis while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Santiago by bus?

Bus from Santiago to Florianópolis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Santiago

Buses Leaving from Santiago

Buses Going to Santiago

Popular Buses Connecting Florianópolis

Buses Leaving from Florianópolis

Buses Going to Florianópolis