Bus Tickets from Santiago, BR to Itajaí

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TodayMay 23
TomorrowMay 24
SunMay 25
MonMay 26
from US$68
TueMay 27
WedMay 28
ThuMay 29
FriMay 30

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: May 26 at
    Departure city: Santiago
    Departure location: Estação Rodoviária De Santiago
    Arrival time: May 27 at
    Destination city: Itajaí
    Destination location: Itajaí Bus Terminal
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:
  • Departure time: May 26 at
    Departure city: Santiago
    Departure location: Estação Rodoviária De Santiago
    Arrival time: May 27 at
    Destination city: Itajaí
    Destination location: Itajaí Bus Terminal
    Operated by: União Santa CruzUnião Santa Cruz
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 6:55 AM -03.

Prices and availability are subject to change.

Accepted payments

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Bus Santiago to Itajaí: Trip Overview

Average Ticket PriceUS$69
Average Bus Trip Duration17h 40m
Number of daily buses1
Earliest bus departure3:00pm
Distance656 km

Santiago to Itajaí Bus

Busbud helps you find a bus from Santiago to Itajaí. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Santiago to Itajaí.

Whether it is cheap bus tickets or more luxurious buses going to Itajaí from Santiago, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Santiago, BR - Itajaí

  1. How long does it take to get to Itajaí from Santiago by bus?

    The trip from Santiago to Itajaí will take on average 17h 40m. For the shortest travel time, select the fastest bus available, which will take you to Itajaí in about 17h 40m.

  2. What is the distance between Santiago and Itajaí?

    It's about 659 km (409 miles) from Santiago to Itajaí.

  3. What are the departure and arrival locations for buses traveling from Santiago to Itajaí?

    Buses traveling this route start their trip at Santiago Onibus, in Santiago, and end it at Itajaí Bus Terminal, in Itajaí.

  4. What is the cheapest way to travel from Santiago to Itajaí?

    The least expensive way to go from Santiago to Itajaí would be going by bus. With a starting ticket price of US$68, this bus becomes your top pick for this journey.

  5. How much is the bus from Santiago to Itajaí?

    Taking the bus from Santiago to Itajaí costs on average US$69.

  6. Is it possible to travel by overnight bus from Santiago to Itajaí?

    Yes! Catch buses leaving from Santiago until 3:00pm and reaching Itajaí on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-21
No data
05-22
US$59
Today
No data
05-24
No data
05-25
No data
05-26
US$59
05-27
No data
05-28
No data
busbud logoThe cheapest trip from Santiago to Itajaí was searched and found on May 26, 2025 with a price of US$59

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago to Itajaí, as early as possible.

You can expect to pay from US$59 to US$75 for a bus ticket from Santiago to Itajaí based on the last 2 days. You can expect to find the cheapest price for the trip at US$59 which is on 2025-05-26.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Santiago and Itajaí!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Santiago to Itajaí.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Santiago to Itajaí.

Make a music playlist for your bus ride from Santiago to Itajaí, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Santiago by bus?

Bus from Santiago to Itajaí

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