Bus Tickets from St Louis, MO to Chicago, IL

Find affordable bus tickets from St Louis, MO to Chicago, IL with flexible options. Book your trip now

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TodayDec 11
TomorrowDec 12
from $81
FriDec 13
from $114
SatDec 14
from $65
SunDec 15
from $76
MonDec 16
from $66
TueDec 17
from $65
WedDec 18
from $73

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: December 12 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: December 12 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: December 12 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: December 13 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: December 12 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: December 12 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: December 12 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: December 13 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: December 12 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: December 12 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Today at 5:01 PM CST.

Prices and availability are subject to change.

Bus St Louis to Chicago: Trip Overview

Average Ticket Price$76
Average Bus Trip Duration9h 5m
Number of daily buses1
Earliest bus departure12:50am
Distance422 km
Latest bus departure11:15pm

St Louis to Chicago Buses

Busbud helps you find a bus from St Louis to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from St Louis to Chicago.

Whether it is cheap bus tickets or more luxurious buses going to Chicago from St Louis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip St Louis - Chicago

  1. How long is the trip from St Louis to Chicago by bus?

    The typical travel time from St Louis to Chicago by bus is around 9h 5m. For the shortest travel time, select the fastest bus available, which will take you to Chicago in about 5h 15m.

  2. What is the travel distance from St Louis to Chicago?

    The distance between St Louis and Chicago is around 419 km (260 miles).

  3. How many buses make the trip between St Louis and Chicago each day?

    A Greyhound bus travels from St Louis to Chicago only once a day, at 12:50am. It typically leaves at 12:50am and is operated by Greyhound.

  4. What time does the first bus depart from St Louis to Chicago, and when is the last one?

    The first bus starts running at 12:50am, and the last one leaves at 11:15pm. To ensure a smooth trip, consider arriving at the station early for check-in.

  5. What are the departure and arrival locations for buses traveling from St Louis to Chicago?

    Buses traveling this route start their trip at Gateway Station, in St Louis, and end it at Downtown Greyhound Station, in Chicago.

  6. How much does the bus ticket cost from St Louis to Chicago?

    The bus fare from St Louis to Chicago is approximately $76.

  7. Is there an overnight bus from St Louis to Chicago?

    Yes! Catch buses leaving from St Louis until 11:15pm and reaching Chicago on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12-09
$101
12-10
$104
Today
$104
12-12
$70
12-13
$104
12-14
$54
12-15
$66
12-16
$56
%{brand}s logoThe cheapest trip from St Louis to Chicago was searched and found on Dec 14, 2024 with a price of $54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to Chicago, as early as possible.

You can expect to pay from $54 to $307 for a bus ticket from St Louis to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $54 which is on 2024-12-14.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between St Louis and Chicago!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from St Louis to Chicago.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from St Louis to Chicago.

Make a music playlist for your bus ride from St Louis to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to St Louis by bus?

Bus from St Louis to Chicago

You can also go to Chicago by train

Train from St Louis to Chicago

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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