Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | Buffalo, NY (181 Ellicott St, Buffalo, NY 14203, United States) | No tags | ||||
Greyhound + FlixBus | Bus | Gateway Station | Buffalo (BUF) Airport | No tags | ||||
Greyhound + FlixBus | Bus | Gateway Station | Buffalo (BUF) Airport | No tags | ||||
| Bus | Gateway Station | Niagara Frontier Transportation Authority | No tags | ||||
| Bus | Gateway Station | Buffalo, NY (181 Ellicott St, Buffalo, NY 14203, United States) | No tags |
Compare 2 ways to go from St. Louis to Buffalo
Among the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 1 day, 8 hours 45 minutes, and with fares starting at just $180, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Buffalo?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Compare bus companies
Based on 87413 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $180
Frequently asked questions about travelling from St. Louis to Buffalo, NY by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from St. Louis to Buffalo?
The cheapest bus tickets from St. Louis to Buffalo start from $180. The average price for this route is around $203. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Buffalo?
The average bus travel time from St. Louis to Buffalo is 1d 8h, covering a distance of 1065 km. The quickest bus can get you there in 1d 1h and is operated by Greyhound.
Which bus companies service the St. Louis to Buffalo route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from St. Louis to Buffalo?
The earliest bus departs from St. Louis to Buffalo at 2:00am. And the latest bus departs at 1:55pm.
What are the CO₂ emissions for the bus trip from St. Louis to Buffalo?
A bus trip from St. Louis to Buffalo generates an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Buffalo, NY was searched and found on Dec 4, 2025 with a price of $169To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Buffalo, NY, as early as possible.
What's the cheapest way to go from St. Louis to Buffalo, NY?
The bus is the cheapest travel choice for this destination
