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- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
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Bus Tampa to Panama City, US: Trip Overview
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Tampa to Panama City Bus
Busbud helps you find a bus from Tampa to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Tampa to Panama City.
Whether it is cheap bus tickets or more luxurious buses going to Panama City from Tampa, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Tampa and Panama City?
Frequently asked questions on the trip Tampa - Panama City, US
What is the travel distance from Tampa to Panama City?
The distance between Tampa and Panama City is approximately 398 km (247 miles).
What are the departure and arrival locations for buses traveling from Tampa to Panama City?
Buses departing from Tampa 13th Avenue Bus Stop (McDonald's) in Tampa will take you to Panama City Greyhound Bus Station in Panama City.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Panama City, US, as early as possible.
You can expect to pay from US$40 to US$86 for a bus ticket from Tampa to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$40 which is on 2025-07-29.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tampa and Panama City!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Tampa to Panama City.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tampa to Panama City.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tampa to Panama City.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top travelled bus routes
Why choose Busbud?
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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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