How much is the bus ticket from Chicago to Jefferson City?

The cheapest coach tickets from Chicago to Jefferson City start from £39. The average price for this route is around £60. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from Chicago to Jefferson City?

The average bus journey time from Chicago to Jefferson City is 16h 20m, covering a distance of 324 miles. The fastest bus can take you there in 16h 20m and is operated by Greyhound .

Which bus companies service the Chicago to Jefferson City route?

Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Chicago to Jefferson City?

The earliest bus departs from Chicago to Jefferson City at 00:15. And the latest bus departs at 23:40.

What are the CO₂ emissions for the bus trip from Chicago to Jefferson City?

A bus journey from Chicago to Jefferson City produces an estimated 13 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Which is the best bus company from Chicago to Jefferson City?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87393 reviews.

Which company has the best Wi-Fi from Chicago to Jefferson City?

Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company offers the most punctual service from Chicago to Jefferson City?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Chicago to Jefferson City?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Chicago to Jefferson City from £45 | Refundable Tickets

Next bus departures

Next departures from Chicago to Jefferson City on 2 December
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	22:30	Chicago 95Th & Dan Ryan	17h 30m	16:00	Jefferson City	CheapestFastest
Bus	21:40	Downtown Greyhound Station	18h 20m	16:00	Jefferson City	No tags
Bus	22:00	537-517 W. Jackson Blvd	18h	16:00	Jefferson City	No tags

Next departures from Chicago to Jefferson City on 3 December
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	22:30	Chicago 95Th & Dan Ryan	17h 30m	16:00	Jefferson City	CheapestFastest
Bus	21:40	Downtown Greyhound Station	18h 20m	16:00	Jefferson City	No tags
Bus	22:00	537-517 W. Jackson Blvd	18h	16:00	Jefferson City	No tags

Next departures from Chicago to Jefferson City on 4 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	22:30	Chicago 95Th & Dan Ryan	17h 30m	16:00	Jefferson City	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	00:40	Chicago 95Th & Dan Ryan	15h 20m	16:00	Jefferson City	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	00:15	Downtown Greyhound Station	15h 45m	16:00	Jefferson City	No tags
	Bus	21:40	Downtown Greyhound Station	18h 20m	16:00	Jefferson City	No tags
	Bus	22:00	537-517 W. Jackson Blvd	18h	16:00	Jefferson City	No tags

Next departures from Chicago to Jefferson City on 5 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	22:30	Chicago 95Th & Dan Ryan	17h 30m	16:00	Jefferson City	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	00:40	Chicago 95Th & Dan Ryan	15h 20m	16:00	Jefferson City	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	00:15	Downtown Greyhound Station	15h 45m	16:00	Jefferson City	No tags
	Bus	21:40	Downtown Greyhound Station	18h 20m	16:00	Jefferson City	No tags
	Bus	22:00	537-517 W. Jackson Blvd	18h	16:00	Jefferson City	No tags

Next departures from Chicago to Jefferson City on 6 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	22:30	Chicago 95Th & Dan Ryan	17h 30m	16:00	Jefferson City	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	00:40	Chicago 95Th & Dan Ryan	15h 20m	16:00	Jefferson City	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	00:15	Downtown Greyhound Station	15h 45m	16:00	Jefferson City	No tags
	Bus	21:40	Downtown Greyhound Station	18h 20m	16:00	Jefferson City	No tags
	Bus	22:00	537-517 W. Jackson Blvd	18h	16:00	Jefferson City	No tags

Next departures from Chicago to Jefferson City on 7 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	22:30	Chicago 95Th & Dan Ryan	17h 30m	16:00	Jefferson City	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	00:40	Chicago 95Th & Dan Ryan	15h 20m	16:00	Jefferson City	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	00:15	Downtown Greyhound Station	15h 45m	16:00	Jefferson City	No tags
	Bus	21:40	Downtown Greyhound Station	18h 20m	16:00	Jefferson City	No tags
	Bus	22:00	537-517 W. Jackson Blvd	18h	16:00	Jefferson City	No tags

Last refresh of the prices: Last Sunday at 17:42 CST.

Compare 2 ways to travel from Chicago to Jefferson City

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Jefferson City. The journey takes about 7 hours 46 minutes and with fares starting at just £38, it presents an excellent value for a comfortable ride.

2train per day

7h 46mAverage duration

330 milesDistance

48kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£39 - £119	Average duration16h 20m	CO₂ emissions 13kg CO₂e
Train	Average price£38 - £142	Average duration7h 46m	CO₂ emissions 48kg CO₂e

Compare bus companies

Greyhound

3.5/587,412 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

FlixBus

3.5/511,501 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling by bus from Chicago to Jefferson City, MO

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from Chicago to Jefferson City?
The cheapest coach tickets from Chicago to Jefferson City start from £39. The average price for this route is around £60. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Chicago to Jefferson City?
The average bus journey time from Chicago to Jefferson City is 16h 20m, covering a distance of 324 miles. The fastest bus can take you there in 16h 20m and is operated by Greyhound.
Which bus companies service the Chicago to Jefferson City route?
Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Chicago to Jefferson City?
The earliest bus departs from Chicago to Jefferson City at 00:15. And the latest bus departs at 23:40.
What are the CO₂ emissions for the bus trip from Chicago to Jefferson City?
A bus journey from Chicago to Jefferson City produces an estimated 13 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Chicago to Jefferson City?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87393 reviews.
Which company has the best Wi-Fi from Chicago to Jefferson City?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Chicago to Jefferson City?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Jefferson City?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

30/11

£154

01/12

£117

Today

£60

03/12

£78

04/12

£59

05/12

£60

06/12

£68

07/12

£69

The cheapest trip from Chicago to Jefferson City, MO was searched and found on 4 Dec 2025 with a price of £59

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Jefferson City, MO as early as possible.

You can expect to pay from £59 to £157 for a bus ticket from Chicago to Jefferson City, MO based on the last 2 days. You can expect to find the cheapest price for the trip at £59, which is on 2025-12-04.