Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Chicago 95Th & Dan Ryan | Jefferson City | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Chicago 95Th & Dan Ryan | Jefferson City | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Jefferson City | No tags | ||||
| Bus | Downtown Greyhound Station | Jefferson City | No tags | ||||
| Bus | 537-517 W. Jackson Blvd | Jefferson City | No tags |
Last refresh of the prices: Yesterday at 20:52 CST.
Compare 2 ways to travel from Chicago to Jefferson City
Among the sustainable travel choices, the train stands out as a good way to reach Jefferson City. The journey takes about 7 hours 46 minutes and with fares starting at just £38, it presents an excellent value for a comfortable ride.
Compare bus companies
Frequently asked questions about travelling by bus from Chicago to Jefferson City, MO
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Chicago to Jefferson City?
The cheapest coach tickets from Chicago to Jefferson City start from £39. The average price for this route is around £59. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Chicago to Jefferson City?
The average bus journey time from Chicago to Jefferson City is 16h 20m, covering a distance of 324 miles. The fastest bus can take you there in 16h 20m and is operated by Greyhound.
Which bus companies service the Chicago to Jefferson City route?
What is the earliest and latest departure time for the bus from Chicago to Jefferson City?
The earliest bus departs from Chicago to Jefferson City at 00:15. And the latest bus departs at 23:40.
What are the CO₂ emissions for the bus trip from Chicago to Jefferson City?
A bus journey from Chicago to Jefferson City produces an estimated 13 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Chicago to Jefferson City?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which company has the best Wi-Fi from Chicago to Jefferson City?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Chicago to Jefferson City?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Jefferson City?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Jefferson City, MO was searched and found on 8 Dec 2025 with a price of £55To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Jefferson City, MO as early as possible.
You can expect to pay from £55 to £88 for a bus ticket from Chicago to Jefferson City, MO based on the last 2 days. You can expect to find the cheapest price for the trip at £55, which is on 2025-12-08.
