Bus Tickets from Chicago to Jefferson City (MO)

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Compare 2 ways to go from Chicago to Jefferson City.

Average Price$59 - $151Average Duration18h 45m
13kg CO₂e5 out of 5 stars
Most eco-friendly
Average Price$49 - $153Average Duration10h 21m
48kg CO₂e1 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the train from Chicago to Jefferson City

Among the sustainable travel choices, the train stands out as the good way to reach Jefferson City. The journey takes about 10 hours 21 minutes and with fares starting at just $49, it presents an excellent value for a comfortable ride.

2train per day
10h 21mAverage Duration
$49Cheapest ticket
48kgCO₂ emissions

Bus Chicago to Jefferson City: Trip Overview

Average ticket price$97
Average bus trip duration18h 45m
Number of daily buses3
Earliest bus departure9:45pm
Distance330 miles (532 km)
Latest bus departure10:30pm

Chicago to Jefferson City Bus

With Busbud, comparing and booking tickets for a bus from Chicago to Jefferson City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Chicago to Jefferson City.

Discover how much the bus trip from Chicago to Jefferson City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Chicago - Jefferson City (MO)

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/29
$69
05/30
$45
Today
$89
06/01
$90
06/02
$51
06/03
No data
06/04
$87
06/05
$91
busbud logoThe cheapest trip from Chicago to Jefferson City was searched and found on May 30, 2025 with a price of $45

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Jefferson City, as early as possible.

You can expect to pay from $45 to $105 for a bus ticket from Chicago to Jefferson City based on the last 2 days. You can expect to find the cheapest price for the trip at $51 which is on 2025-06-02.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Chicago to Jefferson City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Chicago to Jefferson City.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Chicago to Jefferson City will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to Jefferson City.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Chicago by bus?

Bus from Chicago to Jefferson City

You can also go to Jefferson City by train

Train from Chicago to Jefferson City

Why choose Busbud?

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