Find coaches from New Orleans to Knoxville, TN

Next departures

Next departures from New Orleans to Knoxville on 11 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
New Orleans Bus Station
Knoxville Bus StationCheapestFastest

Last refresh of the prices: Yesterday at 09:09 CDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus New Orleans to Knoxville, TN: Trip Overview

Average ticket priceUS$99
Average bus trip duration1d 2h
Number of daily buses2
Earliest bus departure08:20
Distance550 miles
Latest bus departure23:15

New Orleans to Knoxville Bus

Busbud helps you find a bus from New Orleans to Knoxville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from New Orleans to Knoxville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Knoxville from New Orleans, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip New Orleans - Knoxville, TN

  1. What's the distance between New Orleans and Knoxville by coach?

    The journey from New Orleans to Knoxville by coach covers an approximate distance of 547 miles (882 km).

  2. How can I travel from New Orleans to Knoxville avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/10
US$269
10/10
No data
Today
US$259
12/10
No data
13/10
No data
14/10
No data
15/10
No data
16/10
No data
busbud logoThe cheapest trip from New Orleans to Knoxville, TN was searched and found on 11 Oct 2025 with a price of US$259

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to Knoxville, TN as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between New Orleans and Knoxville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from New Orleans to Knoxville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from New Orleans to Knoxville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from New Orleans to Knoxville.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to New Orleans by bus?

Bus from Knoxville, TN to New Orleans

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting New Orleans

Buses Leaving from New Orleans

Buses Going to New Orleans

Popular Buses Connecting Knoxville

Buses Leaving from Knoxville

Buses Going to Knoxville