Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Greyhound Bus Stop | San Antonio Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | UCSD Health La Jolla Station | San Antonio Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico | Bus | San Diego (Old Town-FlixBus) | San Antonio Bus Station | No tags | ||||
Greyhound Lines, Inc. + Valley Transit | Bus | Greyhound Bus Stop | San Antonio Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | San Diego (Old Town-FlixBus) | San Antonio Bus Station | No tags |
Last refresh of the prices: Last Friday at 17:45 PST.
Compare 2 ways to travel from San Diego to San Antonio
Among the sustainable travel choices, the train stands out as a good way to reach San Antonio. The journey takes about 1 day, 10 hours 50 minutes and with fares starting at just £207, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Diego and San Antonio?
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C165 Bowie St, San Antonio, 78205
- D4407 S PanAm Expy #101, San Antonio, TX 78225, USA
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Frequently asked questions about travelling by bus from San Diego, CA, US to San Antonio, US
What's the distance between San Diego and San Antonio by coach?
The distance between San Diego and San Antonio by coach is approximately 1125 miles (1815 km).
What is the best way to go from San Diego to San Antonio without flying?
You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego, CA, US to San Antonio, US was searched and found on 25 Nov 2025 with a price of £177To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to San Antonio, US as early as possible.
You can expect to pay from £177 to £177 for a bus ticket from San Diego, CA, US to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at £177, which is on 2025-11-25.
What's the cheapest way to go from San Diego, CA, US to San Antonio, US?
The bus is the cheapest travel choice for this destination
