Next departures to San Diego
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: 17 June atDeparture city: San Luis ObispoDeparture location: Cal Poly Vista Grande Dining ComplexArrival time: 18 June atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: Amtrak
Vehicle: BusDuration: - This trip is recommended because it is the: FastestDeparture time: 17 June atDeparture city: San Luis ObispoDeparture location: AMTRAK StationArrival time: 17 June atDestination city: San DiegoDestination location: Old Town San DiegoOperated by: AmtrakVehicle: BusDuration:
- Departure time: 17 June atDeparture city: San Luis ObispoDeparture location: Cal Poly Vista Grande Dining ComplexArrival time: 17 June atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: BusDuration:
- Departure time: 17 June atDeparture city: San Luis ObispoDeparture location: Cal Poly Vista Grande Dining ComplexArrival time: 17 June atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: BusDuration:
- Departure time: 17 June atDeparture city: San Luis ObispoDeparture location: Cal Poly Vista Grande Dining ComplexArrival time: 17 June atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: BusDuration:
Accepted payments
Compare 2 ways to travel from San Luis Obispo to San Diego
Busbud recommends taking the bus from San Luis Obispo to San DiegoAmong the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 10 hours and with fares starting at just US$45, it presents an excellent value for a comfortable ride.
Bus San Luis Obispo to San Diego: Trip Overview
Compare bus companies
San Luis Obispo to San Diego Bus
With Busbud, comparing and booking tickets for a bus from San Luis Obispo to San Diego is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from San Luis Obispo to San Diego.
Whether it is cheap bus tickets or more luxurious buses going to San Diego from San Luis Obispo, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in San Luis Obispo and San Diego?
Frequently asked questions on the trip San Luis Obispo - San Diego (CA), US
How much is the coach fare from San Luis Obispo to San Diego?
Coach ticket prices from San Luis Obispo to San Diego can start as low as US$45, though the average price for this trip is US$89. The exact cost can vary based on different factors such as the time of travel, the day of the week, and the coach service provider. Compare the prices and amenities offered by each company on Busbud and find the best deals and offers.
How long is the coach ride from San Luis Obispo to San Diego?
The coach journey between San Luis Obispo and San Diego lasts about 10h. If you're looking for the fastest trip, you can get there in just about 7h 45m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.
At what time is the first coach from San Luis Obispo to San Diego?
The first coach from San Luis Obispo to San Diego leaves at 13:20. Times and services may vary during weekends and holidays.
How far is San Diego from San Luis Obispo by coach?
The journey from San Luis Obispo to San Diego by coach covers an approximate distance of 264 miles (426 km).
What is the best way to go from San Luis Obispo to San Diego without flying?
To travel from San Luis Obispo to San Diego without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Luis Obispo to San Diego was searched and found on 15 Jun 2025 with a price of US$65To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to San Diego as early as possible.
You can expect to pay from US$65 to US$99 for a bus ticket from San Luis Obispo to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at US$65, which is on 2025-06-15.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from San Luis Obispo to San Diego.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Luis Obispo to San Diego.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Luis Obispo to San Diego.
Tune out to the fine sounds of your best music playlist on your bus trip from San Luis Obispo to San Diego while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from San Luis Obispo to San Diego?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Buses Connecting San Luis Obispo
Buses Leaving from San Luis Obispo
- Bus from San Luis Obispo to Fremont
- Coach San Luis Obispo - Los Angeles
- Bus San Luis Obispo - San Jose
- San Luis Obispo - San Francisco
- Bus from San Luis Obispo to Salinas
- Coach San Luis Obispo - Monterey
- Bus San Luis Obispo - Paso Robles
- San Luis Obispo - Santa Cruz
- Bus from San Luis Obispo to Chatsworth
- Coach San Luis Obispo - Santa Barbara
Buses Going to San Luis Obispo
- Bus from Fremont to San Luis Obispo
- Coach San Diego - San Luis Obispo
- Bus Oakland - San Luis Obispo
- San Francisco - San Luis Obispo
- Bus from Los Angeles to San Luis Obispo
- Coach Santa Barbara - San Luis Obispo
- Bus San Jose - San Luis Obispo
- Paso Robles - San Luis Obispo
- Bus from Salinas to San Luis Obispo
- Coach Monterey - San Luis Obispo