How much is the bus ticket from San Luis Obispo to San Diego?

The cheapest coach tickets from San Luis Obispo to San Diego start from £27. The average price for this route is around £60. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from San Luis Obispo to San Diego?

The average bus journey time from San Luis Obispo to San Diego is 10h 10m, covering a distance of 263 miles. The fastest bus can take you there in 8h 45m and is operated by FlixBus .

Which bus companies service the San Luis Obispo to San Diego route?

Several major bus companies operate on this route with 4 buses available per day, including services from Amtrak , FlixBus .

What is the earliest and latest departure time for the bus from San Luis Obispo to San Diego?

The earliest bus departs from San Luis Obispo to San Diego at 12:55. And the latest bus departs at 19:25.

What are the CO₂ emissions for the bus trip from San Luis Obispo to San Diego?

A bus journey from San Luis Obispo to San Diego produces an estimated 11 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Which is the best bus company from San Luis Obispo to San Diego?

According to Busbud customers, the highest-rated bus company on this route is Amtrak , with an average rating of 4.1 out of 5 stars based on 5597 reviews.

Which company has the best Wi-Fi from San Luis Obispo to San Diego?

Based on Busbud reviews, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

Which bus company offers the most punctual service from San Luis Obispo to San Diego?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from San Luis Obispo to San Diego?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak , with a cleanliness rating of 4.5 out of 5 stars.

Bus San Luis Obispo to San Diego from £35 | Refundable Tickets

Next departures

Next departures from San Luis Obispo to San Diego on 1 December
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	15:40	Cal Poly Vista Grande Dining Complex	9h 24m	01:04	Santa Fe Depot	Cheapest
	12:55	San Luis Obispo	8h 50m	21:45	UCSD Health La Jolla Station	Fastest
FlixBus + Greyhound Lines, Inc.	12:55	San Luis Obispo	10h 55m	23:50	Greyhound Bus Stop	No tags
	12:55	San Luis Obispo	9h 20m	22:15	Downtown SD (Seaport)	No tags
	10:15	Cal Poly Vista Grande Dining Complex	9h 49m	20:04	Santa Fe Depot	No tags

Next departures from San Luis Obispo to San Diego on 2 December
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	15:40	Cal Poly Vista Grande Dining Complex	9h 24m	01:04	Santa Fe Depot	Cheapest
	12:55	San Luis Obispo	8h 50m	21:45	UCSD Health La Jolla Station	Fastest
FlixBus + Greyhound Lines, Inc.	12:55	San Luis Obispo	10h 55m	23:50	Greyhound Bus Stop	No tags
	12:55	San Luis Obispo	9h 20m	22:15	Downtown SD (Seaport)	No tags
	03:45	Cal Poly Vista Grande Dining Complex	9h 22m	13:07	Santa Fe Depot	No tags

Next departures from San Luis Obispo to San Diego on 3 December
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	12:55	San Luis Obispo	8h 50m	21:45	UCSD Health La Jolla Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	12:55	San Luis Obispo	10h 55m	23:50	Greyhound Bus Stop	No tags
	12:55	San Luis Obispo	9h 20m	22:15	Downtown SD (Seaport)	No tags
	03:45	Cal Poly Vista Grande Dining Complex	9h 22m	13:07	Santa Fe Depot	No tags
	03:45	Cal Poly Vista Grande Dining Complex	9h 22m	13:07	Santa Fe Depot	No tags

Next departures from San Luis Obispo to San Diego on 4 December
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	15:40	Cal Poly Vista Grande Dining Complex	9h 24m	01:04	Santa Fe Depot	Cheapest
	12:55	San Luis Obispo	8h 50m	21:45	UCSD Health La Jolla Station	Fastest
FlixBus + Greyhound Lines, Inc.	12:55	San Luis Obispo	10h 55m	23:50	Greyhound Bus Stop	No tags
	12:55	San Luis Obispo	9h 20m	22:15	Downtown SD (Seaport)	No tags
	03:45	Cal Poly Vista Grande Dining Complex	9h 22m	13:07	Santa Fe Depot	No tags

Next departures from San Luis Obispo to San Diego on 5 December
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
15:40	Cal Poly Vista Grande Dining Complex	9h 24m	01:04	Santa Fe Depot	Cheapest
04:00	AMTRAK Station	8h 53m	12:53	Old Town San Diego	Fastest
03:45	Cal Poly Vista Grande Dining Complex	9h 22m	13:07	Santa Fe Depot	No tags
03:45	Cal Poly Vista Grande Dining Complex	9h 22m	13:07	Santa Fe Depot	No tags
10:15	Cal Poly Vista Grande Dining Complex	9h 49m	20:04	Santa Fe Depot	No tags

Next departures from San Luis Obispo to San Diego on 6 December
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
15:40	Cal Poly Vista Grande Dining Complex	9h 24m	01:04	Santa Fe Depot	Cheapest
04:00	AMTRAK Station	8h 53m	12:53	Old Town San Diego	Fastest
03:45	Cal Poly Vista Grande Dining Complex	9h 22m	13:07	Santa Fe Depot	No tags
03:45	Cal Poly Vista Grande Dining Complex	9h 22m	13:07	Santa Fe Depot	No tags
10:15	Cal Poly Vista Grande Dining Complex	9h 49m	20:04	Santa Fe Depot	No tags

Next departures from San Luis Obispo to San Diego on 7 December
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
03:45	Cal Poly Vista Grande Dining Complex	9h 22m	13:07	Santa Fe Depot	Cheapest
04:00	AMTRAK Station	8h 53m	12:53	Old Town San Diego	Fastest
03:45	Cal Poly Vista Grande Dining Complex	9h 22m	13:07	Santa Fe Depot	No tags
10:15	Cal Poly Vista Grande Dining Complex	9h 49m	20:04	Santa Fe Depot	No tags
10:15	Cal Poly Vista Grande Dining Complex	9h 49m	20:04	Santa Fe Depot	No tags

Last refresh of the prices: Yesterday at 22:54 PST.

Compare 2 ways to travel from San Luis Obispo to San Diego

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 8 hours 44 minutes and with fares starting at just £50, it presents an excellent value for a comfortable ride.

5train per day

8h 44mAverage duration

267 milesDistance

39kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£27 - £101	Average duration10h 10m	CO₂ emissions 11kg CO₂e
Train	Average price£50 - £101	Average duration8h 44m	CO₂ emissions 39kg CO₂e

Where are the popular stops in San Luis Obispo and San Diego?

Stops in San Luis Obispo

A
AMTRAK Station
1730 Santa Rosa St, San Luis Obispo, CA 93401, USA
Visit page
B
San Luis Obispo Bus Stop
1460 Calle Joaquin, San Luis Obispo, CA 93405, USA

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Compare bus companies

Amtrak

4/55,617 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

WiFi3.6

FlixBus

3.5/511,481 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling by bus from San Luis Obispo to San Diego, CA, US

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from San Luis Obispo to San Diego?
The cheapest coach tickets from San Luis Obispo to San Diego start from £27. The average price for this route is around £60. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from San Luis Obispo to San Diego?
The average bus journey time from San Luis Obispo to San Diego is 10h 10m, covering a distance of 263 miles. The fastest bus can take you there in 8h 45m and is operated by FlixBus.
Which bus companies service the San Luis Obispo to San Diego route?
Several major bus companies operate on this route with 4 buses available per day, including services from Amtrak, FlixBus.
What is the earliest and latest departure time for the bus from San Luis Obispo to San Diego?
The earliest bus departs from San Luis Obispo to San Diego at 12:55. And the latest bus departs at 19:25.
What are the CO₂ emissions for the bus trip from San Luis Obispo to San Diego?
A bus journey from San Luis Obispo to San Diego produces an estimated 11 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from San Luis Obispo to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which company has the best Wi-Fi from San Luis Obispo to San Diego?
Based on Busbud reviews, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company offers the most punctual service from San Luis Obispo to San Diego?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Luis Obispo to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

28/11

£53

29/11

£53

Today

£53

01/12

£53

02/12

£53

03/12

£42

04/12

£53

05/12

£53

The cheapest trip from San Luis Obispo to San Diego, CA, US was searched and found on 3 Dec 2025 with a price of £42

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to San Diego, CA, US as early as possible.

You can expect to pay from £42 to £96 for a bus ticket from San Luis Obispo to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at £42, which is on 2025-12-03.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.