How much is the bus ticket from San Luis Obispo to San Diego?

The cheapest bus tickets from San Luis Obispo to San Diego start from $50. The average price for this route is around $111. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from San Luis Obispo to San Diego?

The average bus travel time from San Luis Obispo to San Diego is 10h 10m, covering a distance of 425 km. The quickest bus can get you there in 8h 45m and is operated by FlixBus .

Which bus companies service the San Luis Obispo to San Diego route?

Several major bus companies operate on this route with 4 buses available per day, including services from Amtrak , FlixBus .

What are the earliest and latest departure times for the bus from San Luis Obispo to San Diego?

The earliest bus departs from San Luis Obispo to San Diego at 12:55pm. And the latest bus departs at 7:25pm.

What are the CO₂ emissions for the bus trip from San Luis Obispo to San Diego?

A bus trip from San Luis Obispo to San Diego generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from San Luis Obispo to San Diego?

According to Busbud customers, the highest-rated bus company on this route is Amtrak , with an average rating of 4.1 out of 5 stars based on 5597 reviews.

Which bus company has the best Wi-Fi from San Luis Obispo to San Diego?

Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.

Which bus company has the best on-time performance from San Luis Obispo to San Diego?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from San Luis Obispo to San Diego?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak , with a cleanliness rating of 4.5 out of 5 stars.

Bus San Luis Obispo to San Diego from $65 | Refundable Tickets

Next departures

Next departures for San Luis Obispo to San Diego on November 29
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
3:40pm	Cal Poly Vista Grande Dining Complex	9h 24m	1:04am	Santa Fe Depot	Cheapest
4:00am	AMTRAK Station	8h 53m	12:53pm	Old Town San Diego	Fastest
3:45am	Cal Poly Vista Grande Dining Complex	9h 22m	1:07pm	Santa Fe Depot	No tags
10:15am	Cal Poly Vista Grande Dining Complex	9h 49m	8:04pm	Santa Fe Depot	No tags
1:20pm	Cal Poly Vista Grande Dining Complex	9h 44m	11:04pm	Santa Fe Depot	No tags

Next departures for San Luis Obispo to San Diego on November 30
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
2:40pm	Cal Poly Vista Grande Dining Complex	10h 24m	1:04am	Santa Fe Depot	Cheapest
4:00am	AMTRAK Station	8h 53m	12:53pm	Old Town San Diego	Fastest
3:45am	Cal Poly Vista Grande Dining Complex	9h 22m	1:07pm	Santa Fe Depot	No tags
10:15am	Cal Poly Vista Grande Dining Complex	9h 49m	8:04pm	Santa Fe Depot	No tags
12:20pm	Cal Poly Vista Grande Dining Complex	10h 44m	11:04pm	Santa Fe Depot	No tags

Next departures for San Luis Obispo to San Diego on December 1
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	3:40pm	Cal Poly Vista Grande Dining Complex	9h 24m	1:04am	Santa Fe Depot	Cheapest
	12:55pm	San Luis Obispo	8h 50m	9:45pm	UCSD Health La Jolla Station	Fastest
FlixBus + Greyhound Lines, Inc.	12:55pm	San Luis Obispo	10h 55m	11:50pm	Greyhound Bus Stop	No tags
	12:55pm	San Luis Obispo	9h 20m	10:15pm	Downtown SD (Seaport)	No tags
	10:15am	Cal Poly Vista Grande Dining Complex	9h 49m	8:04pm	Santa Fe Depot	No tags

Next departures for San Luis Obispo to San Diego on December 2
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	3:40pm	Cal Poly Vista Grande Dining Complex	9h 24m	1:04am	Santa Fe Depot	Cheapest
	12:55pm	San Luis Obispo	8h 50m	9:45pm	UCSD Health La Jolla Station	Fastest
FlixBus + Greyhound Lines, Inc.	12:55pm	San Luis Obispo	10h 55m	11:50pm	Greyhound Bus Stop	No tags
	12:55pm	San Luis Obispo	9h 20m	10:15pm	Downtown SD (Seaport)	No tags
	3:45am	Cal Poly Vista Grande Dining Complex	9h 22m	1:07pm	Santa Fe Depot	No tags

Next departures for San Luis Obispo to San Diego on December 3
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	12:55pm	San Luis Obispo	10h 55m	11:50pm	Greyhound Bus Stop	Cheapest
	12:55pm	San Luis Obispo	8h 50m	9:45pm	UCSD Health La Jolla Station	Fastest
	12:55pm	San Luis Obispo	9h 20m	10:15pm	Downtown SD (Seaport)	No tags
	3:45am	Cal Poly Vista Grande Dining Complex	9h 22m	1:07pm	Santa Fe Depot	No tags
	3:45am	Cal Poly Vista Grande Dining Complex	9h 22m	1:07pm	Santa Fe Depot	No tags

Next departures for San Luis Obispo to San Diego on December 4
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	3:40pm	Cal Poly Vista Grande Dining Complex	9h 24m	1:04am	Santa Fe Depot	Cheapest
	12:55pm	San Luis Obispo	8h 50m	9:45pm	UCSD Health La Jolla Station	Fastest
FlixBus + Greyhound Lines, Inc.	12:55pm	San Luis Obispo	10h 55m	11:50pm	Greyhound Bus Stop	No tags
	12:55pm	San Luis Obispo	9h 20m	10:15pm	Downtown SD (Seaport)	No tags
	3:45am	Cal Poly Vista Grande Dining Complex	9h 22m	1:07pm	Santa Fe Depot	No tags

Next departures for San Luis Obispo to San Diego on December 5
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
3:40pm	Cal Poly Vista Grande Dining Complex	9h 24m	1:04am	Santa Fe Depot	Cheapest
4:00am	AMTRAK Station	8h 53m	12:53pm	Old Town San Diego	Fastest
3:45am	Cal Poly Vista Grande Dining Complex	9h 22m	1:07pm	Santa Fe Depot	No tags
3:45am	Cal Poly Vista Grande Dining Complex	9h 22m	1:07pm	Santa Fe Depot	No tags
10:15am	Cal Poly Vista Grande Dining Complex	9h 49m	8:04pm	Santa Fe Depot	No tags

Last refresh of the prices: Yesterday at 7:44 PM PST.

Compare 2 ways to go from San Luis Obispo to San Diego

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 8 hours 44 minutes, and with fares starting at just $93, it presents an excellent value for a comfortable ride.

5train per day

8h 44mAverage Duration

430 kmDistance

39kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$50 - $187	Average Duration10h 10m	CO₂ emissions 11kg CO₂e
Train	Average Price$93 - $186	Average Duration8h 44m	CO₂ emissions 39kg CO₂e

Where are the popular stops in San Luis Obispo and San Diego?

Stops in San Luis Obispo

A
AMTRAK Station
1730 Santa Rosa St, San Luis Obispo, CA 93401, USA
Visit page
B
San Luis Obispo Bus Stop
1460 Calle Joaquin, San Luis Obispo, CA 93405, USA

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Compare bus companies

Amtrak

4/55,611 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

FlixBus

3.5/511,470 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from San Luis Obispo to San Diego, CA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from San Luis Obispo to San Diego?
The cheapest bus tickets from San Luis Obispo to San Diego start from $50. The average price for this route is around $111. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Luis Obispo to San Diego?
The average bus travel time from San Luis Obispo to San Diego is 10h 10m, covering a distance of 425 km. The quickest bus can get you there in 8h 45m and is operated by FlixBus.
Which bus companies service the San Luis Obispo to San Diego route?
Several major bus companies operate on this route with 4 buses available per day, including services from Amtrak, FlixBus.
What are the earliest and latest departure times for the bus from San Luis Obispo to San Diego?
The earliest bus departs from San Luis Obispo to San Diego at 12:55pm. And the latest bus departs at 7:25pm.
What are the CO₂ emissions for the bus trip from San Luis Obispo to San Diego?
A bus trip from San Luis Obispo to San Diego generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from San Luis Obispo to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from San Luis Obispo to San Diego?
Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from San Luis Obispo to San Diego?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Luis Obispo to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-26

$98

11-27

$98

Today

$98

11-29

$98

11-30

$98

12-01

$98

12-02

$98

12-03

$78

The cheapest trip from San Luis Obispo to San Diego, CA, US was searched and found on Dec 3, 2025 with a price of $78

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to San Diego, CA, US, as early as possible.

You can expect to pay from $78 to $169 for a bus ticket from San Luis Obispo to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $78 which is on 2025-12-03.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.