Find coaches from St. Louis to San Antonio, US

Next departures

Next departures from St. Louis to San Antonio on 27 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc. + Valley Transit
Gateway Station
San Antonio Bus StationCheapestFastest
Greyhound Lines, Inc. + Greyhound Lines Mexico
Gateway Station
San Antonio Bus StationNo tags
Greyhound Lines, Inc. + Valley Transit
Gateway Station
San Antonio Bus StationNo tags
Greyhound Lines, Inc.
Gateway Station
San Antonio Bus StationNo tags

Last refresh of the prices: Today at 11:25 CDT.

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Compare 2 ways to travel from St. Louis to San Antonio

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach San Antonio. The journey takes about 22 hours 30 minutes and with fares starting at just US$75, it presents an excellent value for a comfortable ride.

5bus per day
22h 30mAverage duration
791 milesDistance
32kgCO₂ emissions
Bus
Average priceUS$75 - US$296Average duration22h 30m
32kg CO₂e
Train
Average priceUS$112 - US$276Average duration1d 2h
116kg CO₂e

Bus St. Louis to San Antonio, US: Trip Overview

Average ticket priceUS$126
Average bus trip duration22h 30m
Number of daily buses5
Earliest bus departure01:00
Distance791 miles
Latest bus departure16:30

St. Louis to San Antonio Bus

With Busbud, comparing and booking tickets for a bus from St. Louis to San Antonio is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from St. Louis to San Antonio will be provided by the most trusted bus companies.

Discover how much the bus trip from St. Louis to San Antonio will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip St. Louis - San Antonio, US

  1. How far is San Antonio from St. Louis by coach?

    The distance between St. Louis and San Antonio by coach is approximately 793 miles (1278 km).

  2. What is the best way to go from St. Louis to San Antonio without flying?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
24/10
US$190
25/10
US$165
Today
US$149
27/10
US$157
28/10
US$68
29/10
US$77
30/10
US$71
31/10
US$99
busbud logoThe cheapest trip from St. Louis to San Antonio, US was searched and found on 28 Oct 2025 with a price of US$68

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to San Antonio, US as early as possible.

You can expect to pay from US$68 to US$190 for a bus ticket from St. Louis to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$68, which is on 2025-10-28.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from St. Louis to San Antonio.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from St. Louis to San Antonio, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from St. Louis to San Antonio will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St. Louis to San Antonio.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from St. Louis to San Antonio, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St. Louis by bus?

Bus from San Antonio, US to St. Louis

You can also go to San Antonio, US by train

Train from St. Louis to San Antonio, US

Why choose Busbud?

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