Bus Tickets from St Louis to San Antonio, US

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TodayJul 9
from $169
TomorrowJul 10
from $137
FriJul 11
from $143
SatJul 12
from $140
SunJul 13
MonJul 14
from $119
TueJul 15
from $107
WedJul 16

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 10 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: July 12 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
    FlixBus + Greyhound Lines, Inc. + Greyhound Lines Mexico
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 10 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: July 11 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc. + Valley Transit
    FlixBus + Greyhound Lines, Inc. + Valley Transit
    Vehicle: BusDuration:
  • Departure time: July 10 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: July 10 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc. + Greyhound Lines Mexico
    Greyhound Lines, Inc. + Greyhound Lines Mexico
    Vehicle: BusDuration:
  • Departure time: July 10 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: July 11 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus + Greyhound Lines Mexico
    Greyhound Lines, Inc. + FlixBus + Greyhound Lines Mexico
    Vehicle: BusDuration:
  • Departure time: July 10 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: July 11 at
    Destination city: San Antonio
    Destination location: San Antonio Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc. + Valley Transit
    FlixBus + Greyhound Lines, Inc. + Valley Transit
    Vehicle: BusDuration:

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Compare 2 ways to go from St Louis to San Antonio.

Bus
Average Price$93 - $387Average Duration22h 15m
32kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$112 - $228Average Duration1d 2h
116kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St Louis to San Antonio

Among the sustainable travel choices, the bus stands out as the good way to reach San Antonio. The journey takes about 22 hours 15 minutes and with fares starting at just $93, it presents an excellent value for a comfortable ride.

4bus per day
22h 15mAverage Duration
$93Cheapest ticket
32kgCO₂ emissions

Bus St. Louis to San Antonio: Trip Overview

Average ticket price$143
Average bus trip duration22h 15m
Number of daily buses4
Earliest bus departure1:35am
Distance791 miles (1275 km)
Latest bus departure11:30pm

St Louis to San Antonio Bus

With Busbud, comparing and booking tickets for a bus from St Louis to San Antonio is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from St Louis to San Antonio will be provided by the most trusted bus companies.

Discover how much the bus trip from St Louis to San Antonio will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip St Louis - San Antonio, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/07
$169
07/08
No data
Today
No data
07/10
No data
07/11
No data
07/12
No data
07/13
No data
07/14
No data
busbud logoThe cheapest trip from St. Louis to San Antonio was searched and found on Jul 7, 2025 with a price of $169

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to San Antonio, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from St Louis to San Antonio.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from St Louis to San Antonio, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from St Louis to San Antonio will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St Louis to San Antonio.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to St. Louis by bus?

Bus from St. Louis to San Antonio

You can also go to San Antonio by train

Train from St. Louis to San Antonio

Why choose Busbud?

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