- Antofagasta to La Serena buses
Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Terminal de Buses Cardenal Carlos Oviedo Cavada) | La Serena (Bus terminal La Serena) | Cheapest | |||||
![]() | Terminal Carlos Oviedo Cavada | Terminal de Buses La Serena | Fastest | |||||
![]() | Terminal Carlos Oviedo Cavada | Terminal de Buses La Serena | No tags | |||||
![]() | Terminal de Buses Cardenal Carlos Oviedo Cavada) | La Serena (Bus terminal La Serena) | No tags | |||||
![]() | Terminal Carlos Oviedo Cavada | Terminal de Buses La Serena | No tags |
Last refresh of the prices: Last Tuesday at 12:05 PM -03.
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Get from Antofagasta to La Serena
The journey takes about 11 hours 30 minutes, and with fares starting at just US$21, it presents an excellent value for a comfortable ride.
Bus Antofagasta to La Serena, CL: Trip Overview
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Antofagasta to La Serena Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Antofagasta to La Serena.
We make sure you can find a bus service from Antofagasta to La Serena from the most reliable bus companies operating this trip.
Discover how much the bus trip from Antofagasta to La Serena will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Antofagasta and La Serena?
Frequently asked questions on the trip Antofagasta - La Serena, CL
How much does a bus ticket from Antofagasta to La Serena cost?
The bus ticket price from Antofagasta to La Serena starts at US$21. The best way to find cheap bus tickets from Antofagasta to La Serena is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Antofagasta to La Serena?
The average travel time between Antofagasta and La Serena is around 11h 30m, although the fastest bus will take about 10h 40m. This is the time it takes to travel the 704 km that separates the two cities.
How many daily bus connections are there between Antofagasta and La Serena?
The number of buses from Antofagasta to La Serena can differ depending on the day of the week. On average, there are 25 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Antofagasta to La Serena by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Antofagasta to La Serena?
When taking the bus from Antofagasta to La Serena, you can travel comfortably and safely with Pluss Chile, Cikbus Elité, Pullman San Andres.
What are the departure and arrival stations when taking the bus from Antofagasta to La Serena?
Buses travelling between Antofagasta and La Serena leave from Terminal Antofagasta or Av. Pedro Aguirre Cerda, 253 and arrive at Terminal de Buses La Serena, Rotonda La Serena.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Antofagasta to La Serena, CL as early as possible.
You can expect to pay from US$20 to US$53 for a bus ticket from Antofagasta to La Serena, CL based on the last 2 days. You can expect to find the cheapest price for the trip at US$20, which is on 2025-11-01.
Usually Pluss Chile, Pullman San Andres will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Antofagasta to La Serena but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Antofagasta to La Serena, get comfy and count the stars.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Antofagasta to La Serena will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Make a music playlist for your bus ride from Antofagasta to La Serena, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top travelled bus routes
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Popular Buses Connecting Antofagasta
Buses Leaving from Antofagasta
- Bus from Antofagasta to Santiago
- Coach Antofagasta - Sierra Gorda
- Bus Antofagasta - Tocopilla
- Bus from Antofagasta to Coquimbo
- Coach Antofagasta - Vallenar
- Bus Antofagasta - Iquique
- Bus from Antofagasta to Pozo Almonte
- Coach Antofagasta - Caldera
- Bus Antofagasta - La Serena
- Bus from Antofagasta to Valdivia
- Coach Antofagasta - Osorno Province
- Bus Antofagasta - Alto Hospicio
- Bus from Antofagasta to Ovalle
- Coach Antofagasta - San Antonio
- Bus Antofagasta - Calama
Buses Going to Antofagasta
- Bus from Iquique to Antofagasta
- Coach Santiago - Antofagasta
- Bus Tocopilla - Antofagasta
- Bus from Sierra Gorda to Antofagasta
- Coach Taltal - Antofagasta
- Bus Calama - Antofagasta
- Bus from Arica Province to Antofagasta
- Coach Villarrica - Antofagasta
- Bus Pullalli - Antofagasta
- Bus from Copiapo to Antofagasta
- Coach Temuco - Antofagasta
- Bus Pichidangui - Antofagasta
- Bus from Alto Hospicio to Antofagasta
- Coach La Calera - Antofagasta
- Bus La Serena - Antofagasta
Popular Buses Connecting La Serena
Buses Leaving from La Serena
- Bus from La Serena to Coquimbo
- Coach La Serena - Santiago
- Bus La Serena - Temuco
- Bus from La Serena to Ovalle
- Coach La Serena - Antofagasta
- Bus La Serena - Vallenar
- Bus from La Serena to Calama
- Coach La Serena - Los Vilos
- Bus La Serena - Quillota
- Bus from La Serena to El Salvador
- Coach La Serena - Puerto Varas
- Bus La Serena - Villarrica
- Bus from La Serena to Linares
- Coach La Serena - Osorno Province
- Bus La Serena - Tongoy
Buses Going to La Serena
- Bus from Santiago to La Serena
- Coach Ovalle - La Serena
- Bus Copiapo - La Serena
- Bus from Calama to La Serena
- Coach Temuco - La Serena
- Bus Valparaiso - La Serena
- Bus from San Antonio to La Serena
- Coach Baquedano - La Serena
- Bus Antofagasta - La Serena
- Bus from Pullalli to La Serena
- Coach Osorno Province - La Serena
- Bus Caldera - La Serena
- Bus from Taltal to La Serena
- Coach Los Vilos - La Serena
- Bus Concon - La Serena






