Bus from Antofagasta to La Serena, CL: Tickets & Schedules

Next bus departures

Next departures for Antofagasta to La Serena on December 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Cikbus ElitéBus
Terminal Antofagasta
Terminal de Buses La SerenaCheapest
Pluss ChileBus
Terminal Antofagasta
Terminal de Buses La SerenaFastest
Cikbus ElitéBus
Terminal Antofagasta
Terminal de Buses La SerenaNo tags
Pluss ChileBus
Terminal Antofagasta
Terminal de Buses La SerenaNo tags
Pullman San AndrésBus
Terminal Carlos Oviedo Cavada
Terminal de Buses La SerenaNo tags

Last refresh of the prices: Yesterday at 7:11 PM -03.

Get from Antofagasta to La Serena

This route is served by bus only

The journey takes about 11 hours 30 minutes and with fares starting at just $21, it presents an excellent value for a comfortable ride.

27bus per day
11h 30mAverage Duration
438 milesDistance
18kgCO₂ emissions

Frequently asked questions about traveling from Antofagasta to La Serena, CL by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Antofagasta to La Serena?

    The cheapest bus tickets from Antofagasta to La Serena start from $21. The average price for this route is around $42. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Antofagasta to La Serena?

    The average bus trip duration from Antofagasta to La Serena is 11h 30m, covering a distance of 438 miles (705 km). The quickest bus can get you there in 10h 40m and is operated by Cikbus Elité.

  3. Which bus companies service the Antofagasta to La Serena route?

    Several major bus companies operate on this route with 27 buses available per day, including services from Pluss Chile, Pullman San Andres, Cikbus Elité, Buses Andimar, Clikbus.

  4. What is the earliest and latest departure time for the bus from Antofagasta to La Serena?

    The earliest bus departs from Antofagasta to La Serena at 12:05am. And the latest bus departs at 11:55pm.

  5. What are the CO₂ emissions for the bus trip from Antofagasta to La Serena?

    A bus trip from Antofagasta to La Serena generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Antofagasta to La Serena?

    According to Busbud customers, the highest-rated bus company on this route is Clikbus, with an average rating of 4.3 out of 5 stars based on 3 reviews.

  7. Which bus company has the best Wi-Fi from Antofagasta to La Serena?

    Based on reviews on Busbud, the bus company Pluss Chile has the best Wi-Fi rating with a score of 1.6.

  8. Which bus company has the most timely service from Antofagasta to La Serena?

    According to Busbud traveller reviews, the most timely bus company on this route is Clikbus, with a punctuality rating of 5.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Antofagasta to La Serena?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Pluss Chile, with a cleanliness rating of 4.6 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/26
$28
11/27
$20
Today
$29
11/29
$27
11/30
$28
12/01
$20
12/02
$20
12/03
$20
busbud logoThe cheapest trip from Antofagasta to La Serena, CL was searched and found on Dec 3, 2025 with a price of $20

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Antofagasta to La Serena, CL, as early as possible.

You can expect to pay from $20 to $57 for a bus ticket from Antofagasta to La Serena, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $20 which is on 2025-12-03.

Usually Pullman San Andres, Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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