Bus Tickets from Antofagasta to La Serena

Easily compare and book your next trip with Busbud

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayFeb 14
from $46
TomorrowFeb 15
from $39
SunFeb 16
from $59
MonFeb 17
from $39
TueFeb 18
from $39
WedFeb 19
from $39
ThuFeb 20
from $39
FriFeb 21
from $39

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Few seats left
    Departure time: February 15 at
    Departure city: Antofagasta
    Departure location: Terminal Antofagasta
    Arrival time: February 15 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus Elité / CikturCikbus Elité / Ciktur
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: February 15 at
    Departure city: Antofagasta
    Departure location: Terminal Antofagasta
    Arrival time: February 15 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Few seats left
    Departure time: February 15 at
    Departure city: Antofagasta
    Departure location: Terminal Antofagasta
    Arrival time: February 16 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus Elité / CikturCikbus Elité / Ciktur
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Few seats left
    Departure time: February 15 at
    Departure city: Antofagasta
    Departure location: Terminal Antofagasta
    Arrival time: February 16 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • Departure time: February 15 at
    Departure city: Antofagasta
    Departure location: 5791 Avenida Iquique
    Arrival time: February 15 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: AndimarAndimar
    Vehicle: BusDuration:

Last refresh of the prices: Today at 2:42 PM -03.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Antofagasta to La Serena: Trip Overview

Average Ticket Price$65
Average Bus Trip Duration11h 30m
Number of daily buses35
Earliest bus departure12:15am
Distance705 km
Latest bus departure11:59pm

Antofagasta to La Serena Buses

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Antofagasta to La Serena.

We make sure you can find a bus service from Antofagasta to La Serena from the most reliable bus companies operating this trip.

Discover how much the bus trip from Antofagasta to La Serena will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Antofagasta - La Serena

  1. How long is the bus ride from Antofagasta to La Serena?

    The typical travel time from Antofagasta to La Serena by bus is around 11h 30m. The fastest bus on this trip will get to La Serena in 10h 40m

  2. How far is Antofagasta from La Serena?

    It's about 704 km (437 miles) from Antofagasta to La Serena.

  3. How many times do buses run from Antofagasta to La Serena every day?

    In general, there are about 35 buses operating on this route, provided by Pluss Chile, Cikbus Elité and Pullman San Andres.

  4. What are the departure times for the first and last bus from Antofagasta to La Serena?

    You can catch the first bus starting at 12:15am and the last one until 11:59pm. To ensure a smooth trip, consider arriving at the station early for check-in.

  5. What are the departure and arrival locations for buses traveling from Antofagasta to La Serena?

    Buses departing from Av. Pedro Aguirre Cerda, 253 in Antofagasta will take you to Terminal de Buses La Serena in La Serena.

  6. What is the cheapest way to travel from Antofagasta to La Serena?

    The least expensive option to go from Antofagasta to La Serena would be going by bus. The ticket price for this bus starts at $33, making this your best choice for this trip.

  7. How much does it cost to take the bus from Antofagasta to La Serena?

    You can expect to pay around $65 for the bus ride from Antofagasta to La Serena.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
02-12
$46
02-13
$38
Today
$44
02-15
$38
02-16
$55
02-17
$38
02-18
$38
02-19
$38
%{brand}s logoThe cheapest trip from Antofagasta to La Serena was searched and found on Feb 13, 2025 with a price of $38

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Antofagasta to La Serena, as early as possible.

You can expect to pay from $38 to $89 for a bus ticket from Antofagasta to La Serena based on the last 2 days. You can expect to find the cheapest price for the trip at $38 which is on 2025-02-17.

Usually PlussChile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Antofagasta to La Serena but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Antofagasta to La Serena, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Antofagasta to La Serena will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Antofagasta to La Serena, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Antofagasta by bus?

Bus from Antofagasta to La Serena

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

Popular Buses Connecting Antofagasta

Buses Leaving from Antofagasta

Buses Going to Antofagasta

Popular Buses Connecting La Serena

Buses Leaving from La Serena

Buses Going to La Serena