Find coaches from Antofagasta to La Serena, CL

Find affordable coach tickets from Antofagasta to La Serena, CL with flexible options. Book your journey now

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Today16 Jul
from US$35
Tomorrow17 Jul
from US$30
Fri18 Jul
from US$36
Sat19 Jul
from US$35
Sun20 Jul
from US$21
Mon21 Jul
from US$21
Tue22 Jul
from US$39
Wed23 Jul
from US$21

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 17 July at
    Departure city: Antofagasta
    Departure location: Terminal Antofagasta
    Arrival time: 17 July at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus Elité + Pluss Chile
    Cikbus Elité + Pluss Chile
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 17 July at
    Departure city: Antofagasta
    Departure location: Terminal Carlos Oviedo Cavada
    Arrival time: 18 July at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Pullman San AndrésPullman San Andrés
    Vehicle: BusDuration:
  • Departure time: 17 July at
    Departure city: Antofagasta
    Departure location: Terminal Carlos Oviedo Cavada
    Arrival time: 18 July at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Pullman San AndrésPullman San Andrés
    Vehicle: BusDuration:
  • Departure time: 17 July at
    Departure city: Antofagasta
    Departure location: Terminal Antofagasta
    Arrival time: 17 July at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus ElitéCikbus Elité
    Vehicle: BusDuration:
  • Departure time: 17 July at
    Departure city: Antofagasta
    Departure location: Terminal Antofagasta
    Arrival time: 17 July at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus Elité + Pluss Chile
    Cikbus Elité + Pluss Chile
    Vehicle: BusDuration:

Accepted payments

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Bus Antofagasta to La Serena: Trip Overview

Average ticket priceUS$42
Average bus trip duration11h 30m
Number of daily buses26
Earliest bus departure00:15
Distance438 miles
Latest bus departure23:50

Antofagasta to La Serena Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Antofagasta to La Serena.

We make sure you can find a bus service from Antofagasta to La Serena from the most reliable bus companies operating this trip.

Discover how much the bus trip from Antofagasta to La Serena will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Antofagasta - La Serena, CL

  1. What's the distance between Antofagasta and La Serena by coach?

    The journey from Antofagasta to La Serena by coach covers an approximate distance of 437 miles (704 km).

  2. How can I travel from Antofagasta to La Serena avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
14/07
US$26
15/07
US$26
Today
US$32
17/07
US$35
18/07
US$36
19/07
US$33
20/07
US$20
21/07
US$19
busbud logoThe cheapest trip from Antofagasta to La Serena was searched and found on 21 Jul 2025 with a price of US$19

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Antofagasta to La Serena as early as possible.

You can expect to pay from US$19 to US$52 for a bus ticket from Antofagasta to La Serena based on the last 2 days. You can expect to find the cheapest price for the trip at US$19, which is on 2025-07-21.

Usually Pullman San Andrés will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Antofagasta to La Serena but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Antofagasta to La Serena, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Antofagasta to La Serena will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Antofagasta to La Serena, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Antofagasta by bus?

Bus from Antofagasta to La Serena

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