Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Downtown Greyhound Station | Opelika (4th Street Station) | No tags | ||||
FlixBus + Greyhound | Bus | Chicago 95Th & Dan Ryan | Opelika (4th Street Station) | No tags | ||||
 | Bus | Downtown Greyhound Station | Opelika (4th Street Station) | No tags | ||||
| Bus | 537-517 W. Jackson Blvd | Opelika (4th Street Station) | No tags | ||||
| Bus | Chicago 95Th & Dan Ryan | Opelika (4th Street Station) | No tags |
Get from Chicago to Opelika
The journey takes about 18 hours 40 minutes and with fares starting at just $106, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Opelika?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Stops in Opelika
- A
McDonald's - Opelika
1104 Columbus Pkwy, Opelika, AL 36801, USA
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Frequently asked questions about traveling from Chicago to Opelika by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Opelika?
The cheapest bus tickets from Chicago to Opelika start from $106. The average price for this route is around $160. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Opelika?
The average bus trip duration from Chicago to Opelika is 18h 40m, covering a distance of 649 miles (1046 km). The quickest bus can get you there in 17h 35m and is operated by Greyhound.
Which bus companies service the Chicago to Opelika route?
What is the earliest and latest departure time for the bus from Chicago to Opelika?
The earliest bus departs from Chicago to Opelika at 10:00am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Chicago to Opelika?
A bus trip from Chicago to Opelika generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Chicago to Opelika?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Chicago to Opelika?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Chicago to Opelika?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Opelika?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Opelika was searched and found on Dec 2, 2025 with a price of $122To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Opelika, as early as possible.
