What is the distance between Cincinnati and Buffalo?

About 388 miles (626 km) separate Cincinnati and Buffalo.

What are the departure and arrival stations when taking the bus from Cincinnati to Buffalo?

If you're headed to Buffalo from Cincinnati, chances are that your bus will leave from Greyhound Station and arrive at Buffalo Airport. These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

Bus Cincinnati to Buffalo from $52 | Refundable Tickets

Next bus departures

Next departures for Cincinnati to Buffalo on November 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	4:20am	Cincinnati Bus Station	11h 55m	4:15pm	Niagara Frontier Transportation Authority	CheapestFastest

Next departures for Cincinnati to Buffalo on November 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	4:20am	Cincinnati Bus Station	11h 55m	4:15pm	Niagara Frontier Transportation Authority	CheapestFastest

Last refresh of the prices: Last Monday at 5:19 PM EST.

Compare 2 ways to go from Cincinnati to Buffalo

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Buffalo. The journey takes about 11 hours 55 minutes and with fares starting at just $58, it presents an excellent value for a comfortable ride.

1bus per day

11h 55mAverage Duration

386 milesDistance

16kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$58 - $143	Average Duration11h 55m	CO₂ emissions 16kg CO₂e
Train	Average Price$185 - $273	Average Duration1d 7h	CO₂ emissions 59kg CO₂e

Compare bus companies

Greyhound

3.5/587,384 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,380 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Cincinnati and Buffalo?

Stops in Cincinnati

A - Greyhound Station

B - Northland Blvd

Stops in Buffalo

A - Buffalo Airport

B - Transportation Center

C - Exchange Street Station

Frequently asked questions about traveling from Cincinnati to Buffalo, NY by bus

What is the distance between Cincinnati and Buffalo?
What are the departure and arrival stations when taking the bus from Cincinnati to Buffalo?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/18

$93

11/19

$88

Today

$107

11/21

$95

11/22

No data

11/23

No data

11/24

$58

11/25

$74

The cheapest trip from Cincinnati to Buffalo, NY was searched and found on Nov 24, 2025 with a price of $58

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cincinnati to Buffalo, NY, as early as possible.

You can expect to pay from $58 to $107 for a bus ticket from Cincinnati to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $58 which is on 2025-11-24.