Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Des Moines | La Crosse MTU Transit Center | No tags | ||||
| Bus | Des Moines | 632 17th Street North | No tags |
Get from Des Moines to La Crosse
The journey takes about 14 hours 55 minutes and with fares starting at just $180, it presents an excellent value for a comfortable ride.
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Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Frequently asked questions about traveling from Des Moines to La Crosse, WI by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Des Moines to La Crosse?
The cheapest bus tickets from Des Moines to La Crosse start from $180. The average price for this route is around $180. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Des Moines to La Crosse?
The average bus trip duration from Des Moines to La Crosse is 14h 55m, covering a distance of 192 miles (309 km). The quickest bus can get you there in 14h 55m and is operated by Jefferson Lines.
Which bus companies service the Des Moines to La Crosse route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Des Moines to La Crosse?
The earliest bus departs from Des Moines to La Crosse at 11:30pm. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Des Moines to La Crosse?
A bus trip from Des Moines to La Crosse generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
