How much is the bus ticket from Düsseldorf to Prague?

The cheapest bus tickets from Düsseldorf to Prague start from $39. The average price for this route is around $72. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Düsseldorf to Prague?

The average bus trip duration from Düsseldorf to Prague is 13h 55m, covering a distance of 336 miles (541 km). The quickest bus can get you there in 9h 58m and is operated by RegioJet .

Which bus companies service the Düsseldorf to Prague route?

Several major bus companies operate on this route with 33 buses available per day, including services from FlixBus , RegioJet , Musil Tour , BlaBlaCar Bus , Infobus .

What is the earliest and latest departure time for the bus from Düsseldorf to Prague?

The earliest bus departs from Düsseldorf to Prague at 1:25am. And the latest bus departs at 11:59pm.

What are the CO₂ emissions for the bus trip from Düsseldorf to Prague?

A bus trip from Düsseldorf to Prague generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Düsseldorf to Prague?

According to Busbud customers, the highest-rated bus company on this route is RegioJet , with an average rating of 4.1 out of 5 stars based on 1066 reviews.

Which bus company has the best Wi-Fi from Düsseldorf to Prague?

Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.

Which bus company has the most timely service from Düsseldorf to Prague?

According to Busbud traveller reviews, the most timely bus company on this route is Infobus , with a punctuality rating of 4.3 out of 5 stars.

Which bus company has the cleanest buses from Düsseldorf to Prague?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Infobus , with a cleanliness rating of 4.8 out of 5 stars.

Bus Düsseldorf to Prague from $36 | Refundable Tickets

Next departures

Next departures for Düsseldorf to Prague on January 9
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
10:35pm	ZOB am Hbf	12h 15m	10:50am	Prague (Main Railway Station)	Cheapest
10:00pm	ZOB am Hbf	10h 40m	8:40am	Prague (Central Bus Station Florenc)	Fastest
10:35pm	ZOB am Hbf	15h 10m	1:45pm	PRG Airport	No tags
11:59pm	ZOB am Hbf	16h 41m	4:40pm	PRG Airport	No tags
10:00pm	ZOB am Hbf	13h 30m	11:30am	Prague (Main Station - parking)	No tags

Next departures for Düsseldorf to Prague on January 10
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	6:50pm	Hbf	9h 58m	4:48am	Florenc	CheapestFastest
Flixtrain + Flixbus	8:39am	Hbf	14h 51m	11:30pm	PRG Airport	No tags
	3:45am	ZOB am Hbf	16h 30m	8:15pm	PRG Airport	No tags
Flixtrain + Flixbus	12:39pm	Hbf	15h 56m	4:35am	PRG Airport	No tags
	7:15am	ZOB am Hbf	13h 30m	8:45pm	PRG Airport	No tags

Next departures for Düsseldorf to Prague on January 11
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	6:50pm	Hbf	9h 58m	4:48am	Florenc	CheapestFastest
Flixtrain + Flixbus	8:39am	Hbf	14h 51m	11:30pm	PRG Airport	No tags
	3:45am	ZOB am Hbf	16h 30m	8:15pm	PRG Airport	No tags
Flixtrain + Flixbus	12:39pm	Hbf	15h 56m	4:35am	PRG Airport	No tags
	7:15am	ZOB am Hbf	13h 30m	8:45pm	PRG Airport	No tags

Last refresh of the prices: Yesterday at 4:31 PM CET.

Compare 3 ways to go from Düsseldorf to Prague

We recommend carpooling

Among the sustainable travel choices, the Carpool stands out as the good way to reach Prague. The journey takes about 7 hours 20 minutes and with fares starting at just $47, it presents an excellent value for a comfortable ride.

2carpool per day

7h 20mAverage Duration

343 milesDistance

23kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$39 - $268	Average Duration13h 55m	CO₂ emissions 14kg CO₂e
Train	Average Price$58 - $272	Average Duration12h 4m	CO₂ emissions 13kg CO₂e
Carpool	Average Price$47 - $78	Average Duration7h 20m	CO₂ emissions 23kg CO₂e

Where are the popular stops in Düsseldorf and Prague?

Stops in Düsseldorf

A
ZOB am Hbf
Fernbusbahnhof/Hbf Worringer Str. 140, 40210 Düsseldorf, Germany
Visit page Map
B
Hbf
Konrad-Adenauer-Platz 14, 40210 Düsseldorf, Germany
Visit page Map
C
Bastionstraße, 24
Bastionstraße 24, 40213 Düsseldorf, Germany
Map
D
Kurfürstenstraße
Kurfürstenstraße, 40210 Düsseldorf, Germany
Map
E
Kasernenstraße
Kasernenstraße 3, 40213 Düsseldorf, Germany
Map

Stops in Prague

A
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page Map
B
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page Map
C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
Map
D
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
Visit page Map
E
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page Map
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page Map

Compare bus companies

FlixBus

3.5/511,977 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

RegioJet

4/51,066 reviews

Staff4.5

Timeliness3.9

Cleanliness4.4

Wifi3.8

Musil Tour

BlaBlaCar Bus

3.5/511,362 reviews

Staff4.4

Timeliness3.7

Cleanliness4.3

Wifi2.6

Infobus

4/5494 reviews

Staff4.6

Timeliness4.3

Cleanliness4.8

Wifi3.8

CZ bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Düsseldorf to Prague by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Düsseldorf to Prague?
The cheapest bus tickets from Düsseldorf to Prague start from $39. The average price for this route is around $72. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Düsseldorf to Prague?
The average bus trip duration from Düsseldorf to Prague is 13h 55m, covering a distance of 336 miles (541 km). The quickest bus can get you there in 9h 58m and is operated by RegioJet.
Which bus companies service the Düsseldorf to Prague route?
Several major bus companies operate on this route with 33 buses available per day, including services from FlixBus, RegioJet, Musil Tour, BlaBlaCar Bus, Infobus.
What is the earliest and latest departure time for the bus from Düsseldorf to Prague?
The earliest bus departs from Düsseldorf to Prague at 1:25am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Düsseldorf to Prague?
A bus trip from Düsseldorf to Prague generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Düsseldorf to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1066 reviews.
Which bus company has the best Wi-Fi from Düsseldorf to Prague?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Düsseldorf to Prague?
According to Busbud traveller reviews, the most timely bus company on this route is Infobus, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Düsseldorf to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Infobus, with a cleanliness rating of 4.8 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/07

No data

01/08

$36

Today

$63

01/10

$36

01/11

$42

01/12

$36

01/13

No data

01/14

No data

The cheapest trip from Düsseldorf to Prague was searched and found on Jan 8, 2026 with a price of $36

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Düsseldorf to Prague, as early as possible.

You can expect to pay from $36 to $105 for a bus ticket from Düsseldorf to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $36 which is on 2026-01-10.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.