Next departures for Greensboro to Chicago on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Greensboro Bus Station
Downtown Greyhound Station
CheapestFastest
FlixBus + Greyhound Lines, Inc.
Bus
Greensboro Bus Station
537-517 W. Jackson Blvd
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Greensboro Bus Station
Chicago 95Th & Dan Ryan
No tags
Next departures for Greensboro to Chicago on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Greensboro Bus Station
Chicago 95Th & Dan Ryan
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
Greensboro Bus Station
Chicago 95Th & Dan Ryan
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Greensboro Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Greensboro Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Greensboro Bus Station
Downtown Greyhound Station
No tags
Next departures for Greensboro to Chicago on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Greensboro Bus Station
Chicago 95Th & Dan Ryan
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
Greensboro Bus Station
Chicago 95Th & Dan Ryan
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Greensboro Bus Station
Downtown Greyhound Station
No tags
Bus
Greensboro Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Greensboro Bus Station
Downtown Greyhound Station
No tags
Next departures for Greensboro to Chicago on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Greensboro Bus Station
Chicago 95Th & Dan Ryan
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Greensboro Bus Station
Downtown Greyhound Station
No tags
Bus
Greensboro Bus Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Greensboro Bus Station
Downtown Greyhound Station
No tags
Bus
Greensboro Bus Station
Chicago 95Th & Dan Ryan
No tags
Last refresh of the prices: Last Saturday at 4:26 PM EST.
Compare 2 ways to go from Greensboro to Chicago
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 15 minutes and with fares starting at just $107, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Greensboro, NC to Chicago by bus
How far is Greensboro from Chicago?
About 580 miles (936 km) separate Greensboro and Chicago.
What are the departure and arrival stations when taking the bus from Greensboro to Chicago?
Most of the buses traveling from Greensboro to Chicago leave from Greensboro Station and arrive at Downtown Greyhound Station. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Chicago?
Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Lake Michigan, Navy Pier, Chicago Shakespeare Theater on Navy Pier, Lincoln Park Conservatory and Auditorium Building and Theatre.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/22
$205
11/23
$236
Today
$205
11/25
$281
11/26
$123
11/27
$115
11/28
$162
11/29
No data
The cheapest trip from Greensboro, NC to Chicago was searched and found on Nov 27, 2025 with a price of $115
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greensboro, NC to Chicago, as early as possible.
You can expect to pay from $115 to $304 for a bus ticket from Greensboro, NC to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $115 which is on 2025-11-27.
What's the cheapest way to go from Greensboro, NC to Chicago?
The bus is the cheapest travel choice for this destination