How far is Houston from Knoxville?

The distance separating Houston and Knoxville is 789 miles (1272 km).

What are the departure and arrival stations when taking the bus from Houston to Knoxville?

Most of the buses traveling from Houston to Knoxville leave from Hillcroft Ave & Southwest Freeway and arrive at 100 Kirkwood St. These are the most popular departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

Bus Houston to Knoxville from $117 | Refundable Tickets

Previously seen trips

Next departures for Houston to Knoxville on November 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound	Bus	11:10am	Downtown Gray & Smith	1d 10h	10:20pm	Knoxville Bus Station	No tags
Greyhound + FlixBus	Bus	11:10am	Downtown Gray & Smith	1d 10h	10:20pm	Knoxville Bus Station	No tags
Greyhound + FlixBus	Bus	11:25am	Houston Uptown/Upper Kirby	1d 9h	10:20pm	Knoxville Bus Station	No tags
Greyhound + FlixBus	Bus	2:25pm	Downtown Gray & Smith	1d 7h	10:40pm	Knoxville Bus Station	No tags
FlixBus + Greyhound	Bus	2:25pm	Downtown Gray & Smith	1d 7h	10:40pm	Knoxville Bus Station	No tags

Get from Houston to Knoxville

This route is served by bus only

The journey takes about 1 day, 6 hours 20 minutes and with fares starting at just $74, it presents an excellent value for a comfortable ride.

8bus per day

1d 6hAverage Duration

795 milesDistance

32kgCO₂ emissions

Compare bus companies

Greyhound

3.5/587,371 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,305 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Valley Transit

3/533 reviews

Staff3.8

Timeliness3.4

Cleanliness2.9

Wifi2.3

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Houston and Knoxville?

Stops in Houston

A - Hillcroft Ave & Southwest Freeway

B - Downtown Greyhound Station

C - Harrisburg Greyhound Station

D - Harrisburg Senda Station

E - Clay St & Louisiana St

F - Lockwood Dr & Harvey Wilson Dr

Stops in Knoxville

A - 100 Kirkwood St

Frequently asked questions about traveling from Houston, US to Knoxville, TN by bus

How far is Houston from Knoxville?
What are the departure and arrival stations when taking the bus from Houston to Knoxville?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/12

$119

11/13

$109

Today

$117

11/15

$133

11/16

No data

11/17

No data

11/18

No data

11/19

$134

The cheapest trip from Houston, US to Knoxville, TN was searched and found on Nov 13, 2025 with a price of $109

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Knoxville, TN, as early as possible.

You can expect to pay from $109 to $134 for a bus ticket from Houston, US to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $133 which is on 2025-11-15.