Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | TA Travel Center - Lafayette | St Louis, MO | No tags | ||||
Greyhound + FlixBus | Bus | TA Travel Center - Lafayette | Gateway Station | No tags | ||||
Greyhound + FlixBus | Bus | TA Travel Center - Lafayette | Gateway Station | No tags | ||||
 | Bus | Lafayette Transit System | St Louis, MO | No tags | ||||
| Bus | Lafayette Transit System | Gateway Station | No tags |
Get from Lafayette to St. Louis
The journey takes about 1 day, 1 hour 30 minutes and with fares starting at just $134, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lafayette and St. Louis?
Stops in Lafayette
- A1701 N University Ave, Lafayette, LA 70507, USA
- B
Lafayette A and J Travel Bus Station
100 Lee Ave, Lafayette, LA 70501 - C
Lafayette Bus Stop
2405 Cameron St, Lafayette, LA, USA
Compare bus companies
Frequently asked questions about traveling from Lafayette, LA to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Lafayette to St. Louis?
The cheapest bus tickets from Lafayette to St. Louis start from $134. The average price for this route is around $179. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Lafayette to St. Louis?
The average bus trip duration from Lafayette to St. Louis is 1d 1h, covering a distance of 587 miles (946 km). The quickest bus can get you there in 18h 55m and is operated by FlixBus.
Which bus companies service the Lafayette to St. Louis route?
What is the earliest and latest departure time for the bus from Lafayette to St. Louis?
The earliest bus departs from Lafayette to St. Louis at 1:30am. And the latest bus departs at 10:35pm.
What are the CO₂ emissions for the bus trip from Lafayette to St. Louis?
A bus trip from Lafayette to St. Louis generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Lafayette to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Lafayette to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Lafayette to St. Louis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Lafayette to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lafayette, LA to St. Louis was searched and found on Dec 13, 2025 with a price of $127To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, LA to St. Louis, as early as possible.
