Bus Tickets from Charlotte, NC to St. Louis

Next departures

Next departures for Charlotte to St. Louis on October 27
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Charlotte Bus Station
Gateway StationCheapest
Greyhound Lines, Inc.
Charlotte Bus Station
Gateway StationFastest
FlixBus + Greyhound Lines, Inc.
Charlotte Bus Station
Gateway StationNo tags
Greyhound Lines, Inc.
Charlotte Bus Station
Gateway StationNo tags
Greyhound Lines, Inc.
Charlotte Bus Station
Gateway StationNo tags

Last refresh of the prices: Yesterday at 2:17 AM EDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Charlotte to St. Louis

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 23 hours 5 minutes and with fares starting at just $96, it presents an excellent value for a comfortable ride.

8bus per day
23h 5mAverage Duration
566 milesDistance
23kgCO₂ emissions
Bus
Average Price$96 - $322Average Duration23h 5m
23kg CO₂e
Train
Average Price$300 - $329Average Duration1d 14h
83kg CO₂e

Bus Charlotte, NC to St. Louis: Trip Overview

Average ticket price$145
Average bus trip duration23h 5m
Number of daily buses8
Earliest bus departure12:55am
Distance567 miles (913 km)
Latest bus departure11:40pm

Charlotte to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Charlotte to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Charlotte to St. Louis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Charlotte, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Charlotte, NC - St. Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/24
$150
10/25
$157
Today
$156
10/27
$120
10/28
$76
10/29
$71
10/30
$111
10/31
No data
busbud logoThe cheapest trip from Charlotte, NC to St. Louis was searched and found on Oct 29, 2025 with a price of $71

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlotte, NC to St. Louis, as early as possible.

You can expect to pay from $71 to $192 for a bus ticket from Charlotte, NC to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $71 which is on 2025-10-29.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Charlotte to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Charlotte to St. Louis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Charlotte to St. Louis.

Make a music playlist for your bus ride from Charlotte to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Charlotte, NC to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Charlotte, NC by bus?

Bus from St. Louis to Charlotte, NC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Charlotte

Buses Leaving from Charlotte

Buses Going to Charlotte

Popular Buses Connecting St. Louis

Buses Leaving from St. Louis

Buses Going to St. Louis