Bus Tickets from Milan to Palermo

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TodayMay 15
from $42
TomorrowMay 16
from $92
SatMay 17
SunMay 18
MonMay 19
TueMay 20
WedMay 21
from $61
ThuMay 22
from $81

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: May 16 at
    Departure city: Milan
    Departure location: Milan San Donato Bus Station
    Arrival time: May 17 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • Departure time: May 16 at
    Departure city: Milan
    Departure location: Lampugnano
    Arrival time: May 17 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • Departure time: May 16 at
    Departure city: Milan
    Departure location: Lampugnano bus station
    Arrival time: May 17 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 16 at
    Departure city: Milan
    Departure location: Lampugnano bus station
    Arrival time: May 17 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 16 at
    Departure city: Milan
    Departure location: Milan (San Donato M3)
    Arrival time: May 17 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

Accepted payments

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Compare 2 ways to go from Milan to Palermo.

Bus
Average Price$46 - $292Average Duration1d 1h
22kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average Price$131 - $131Average Duration23h 30m
37kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Milan to Palermo

Among the sustainable travel choices, the carpool stands out as the good way to reach Palermo. The journey takes about 23 hours 30 minutes and with fares starting at just $131, it presents an excellent value for a comfortable ride.

1carpool per day
23h 30mAverage Duration
$131Cheapest ticket
37kgCO₂ emissions

Bus Milan to Palermo: Trip Overview

Average ticket price$113
Average bus trip duration1d 1h
Number of daily buses12
Earliest bus departure3:05am
Distance547 miles (882 km)
Latest bus departure11:50pm

Milan to Palermo Bus

Busbud helps you find a bus from Milan to Palermo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Milan to Palermo from the most reliable bus companies operating this trip.

Discover how much the bus trip from Milan to Palermo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Milan - Palermo

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/13
$85
05/14
$86
Today
$42
05/16
$92
05/17
$89
05/18
$45
05/19
$93
05/20
$93
busbud logoThe cheapest trip from Milan to Palermo was searched and found on May 15, 2025 with a price of $42

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milan to Palermo, as early as possible.

You can expect to pay from $42 to $186 for a bus ticket from Milan to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $45 which is on 2025-05-18.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Milan and Palermo!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Milan to Palermo, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Milan to Palermo will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Milan to Palermo.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Milan to Palermo?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Milan by bus?

Bus from Milan to Palermo

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