Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus Station | Syracuse (Regional Transportation Center) | No tags | ||||
FlixBus + Greyhound | Bus | Bus Station | Syracuse (Regional Transportation Center) | No tags | ||||
Greyhound + FlixBus | Bus | Bus Station | Syracuse (Regional Transportation Center) | No tags | ||||
| Bus | Bus Station | Syracuse (Regional Transportation Center) | No tags | ||||
| Bus | Bus Station | Syracuse (Regional Transportation Center) | No tags |
Get from Myrtle Beach to Syracuse
The journey takes about 23 hours 50 minutes and with fares starting at just $595, it presents an excellent value for a comfortable ride.
Where are the popular stops in Myrtle Beach and Syracuse?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Myrtle Beach to Syracuse, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Myrtle Beach to Syracuse?
The cheapest bus tickets from Myrtle Beach to Syracuse start from $595. The average price for this route is around $595. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Myrtle Beach to Syracuse?
The average bus trip duration from Myrtle Beach to Syracuse is 23h 50m, covering a distance of 664 miles (1070 km). The quickest bus can get you there in 23h 50m and is operated by Greyhound.
Which bus companies service the Myrtle Beach to Syracuse route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Myrtle Beach to Syracuse?
The earliest bus departs from Myrtle Beach to Syracuse at 1:55pm. And the latest bus departs at 1:55pm.
What are the CO₂ emissions for the bus trip from Myrtle Beach to Syracuse?
A bus trip from Myrtle Beach to Syracuse generates an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Myrtle Beach to Syracuse, US was searched and found on Dec 17, 2025 with a price of $221To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to Syracuse, US, as early as possible.
Top traveled bus routes
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Popular bus departures from Myrtle Beach
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