Next departures for Boston to Syracuse on November 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
South Station (Train Terminal)
Amtrak Station
CheapestFastest
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
South Station (Train Terminal)
Amtrak Station
No tags
Peter Pan + New York Trailways
Boston (South Station)
Amtrak Station
No tags
Next departures for Boston to Syracuse on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
South Station (Train Terminal)
Amtrak Station
Cheapest
Boston (South Station)
Syracuse (Regional Transportation Center)
Fastest
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
South Station (Train Terminal)
Amtrak Station
No tags
Next departures for Boston to Syracuse on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
South Station (Train Terminal)
Amtrak Station
Cheapest
Boston (South Station)
Syracuse (Regional Transportation Center)
Fastest
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
South Station (Train Terminal)
Amtrak Station
No tags
Next departures for Boston to Syracuse on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Boston (South Station)
Syracuse (Regional Transportation Center)
Cheapest
39 Dalton St
SYR Airport
Fastest
Greyhound Lines, Inc. + FlixBus
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
Next departures for Boston to Syracuse on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Boston (South Station)
Syracuse (Regional Transportation Center)
Cheapest
39 Dalton St
SYR Airport
Fastest
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
FlixBus + Greyhound Lines, Inc.
151 Steel Pl, Cambridge
Syracuse (Regional Transportation Center)
No tags
Next departures for Boston to Syracuse on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Boston (South Station)
Syracuse (Regional Transportation Center)
Cheapest
39 Dalton St
SYR Airport
Fastest
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
FlixBus + Greyhound Lines, Inc.
151 Steel Pl, Cambridge
Syracuse (Regional Transportation Center)
No tags
Next departures for Boston to Syracuse on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
39 Dalton St
222 Waverly Ave
Cheapest
39 Dalton St
SYR Airport
Fastest
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
FlixBus + Greyhound Lines, Inc.
151 Steel Pl, Cambridge
Syracuse (Regional Transportation Center)
No tags
Next departures for Boston to Syracuse on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Peter Pan + New York Trailways
Boston (South Station)
Amtrak Station
Cheapest
39 Dalton St
SYR Airport
Fastest
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
Boston (South Station)
Syracuse (Regional Transportation Center)
No tags
39 Dalton St
222 Waverly Ave
No tags
Last refresh of the prices: Today at 5:44 AM EST.
Compare 2 ways to go from Boston to Syracuse
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Syracuse. The journey takes about 11 hours 10 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Boston Syracuse recent customer reviews
Absolutely horrible two bus drivers did not show up for work which meant I had two cancellations and 11 hours at the bus terminal
1 out of 5 stars
David F.
The Bus was one hour late. The A/C on the Bus wasn't very effective. In the seats towards the toilet it smelled like urin. Otherwise it was OK. I like taking the Bus.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
With about 2 daily trips between Boston and Syracuse, Ourbus offers competitive fares, clean and comfortable intercity bus travel. Their buses have free WiFi, clean bathrooms, complimentary bottled water, extra legroom and power outlets. They are known for providing excellent customer service, reflecting one of the industry's highest review rates. OurBus does not charge fees to reschedule tickets, which can be changed up to 30 minutes before travel time.
Based on 5593 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $41
Based on 6327 reviews, the company was rated 4 stars on Busbud. Travelers were especially satisfied with the cleanliness and the ticket access but often complained with the wifi. Peter Pan ticket prices on this trip start at $89
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210Syracuse University
D - Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E - New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F - Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Frequently asked questions about traveling from Boston, MA, US to Syracuse, US by bus
What is the travel distance from Boston to Syracuse?
The distance between the two cities is 263 miles (424 km).
What are the departure and arrival stations when taking the bus from Boston to Syracuse?
The majority of buses traveling from Boston to Syracuse start their journey at Back Bay Station and wind up at Regional Transportation Center. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Syracuse?
Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are Onondaga Historical Association Museum, MOST, Webster Pond, Rosamond Gifford Zoo and NBT Bank Stadium.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
$89
11/17
$74
Today
$54
11/19
$54
11/20
$54
11/21
$70
11/22
$66
11/23
$74
The cheapest trip from Boston, MA, US to Syracuse, US was searched and found on Nov 18, 2025 with a price of $54
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Syracuse, US, as early as possible.
You can expect to pay from $54 to $215 for a bus ticket from Boston, MA, US to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $54 which is on 2025-11-19.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Boston, MA, US to Syracuse, US?
The bus is the cheapest travel choice for this destination