Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Chinatown | San Ysidro Bus terminal | Cheapest | ||||
 | Bus | New York Port Authority | San Ysidro Bus terminal | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | New York Port Authority | San Ysidro Bus terminal | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | NYC Midtown (31st St & 8th Ave) | San Ysidro Bus terminal | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Queens Jamaica (44th Pl/Archer Ave) | San Ysidro Bus terminal | No tags |
Last refresh of the prices: Last Thursday at 1:55 PM EST.
Get from New York City to San Ysidro
The journey takes about 3 days, 3 hours 35 minutes and with fares starting at just $434, it presents an excellent value for a comfortable ride.
Where are the popular stops in New York City and San Ysidro?
Stops in New York City
- A
Chinatown
122 Allen St, New York, NY 10002-3004 - B40-42, 625 8th Ave, New York, NY 10018, USA
- C4211 Broadway, New York, NY 10033, USA
- D
11th Ave (between W35th and W36th Street)
428-436 11th Ave, Stop across from Javits Convention Center, New York, NY 10018, USA - E127 E Broadway, New York, NY 10002, USA
- F
34th St & 9th Ave
367 W 34th St, New York, NY 10001, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from New York City to San Ysidro, CA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from New York City to San Ysidro?
The cheapest bus tickets from New York City to San Ysidro start from $434. The average price for this route is around $595. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from New York City to San Ysidro?
The average bus trip duration from New York City to San Ysidro is 3d 3h, covering a distance of 2425 miles (3911 km). The quickest bus can get you there in 2d 19h and is operated by Greyhound.
Which bus companies service the New York City to San Ysidro route?
Several major train operators operate on this route with 10 trains available per day.
What is the earliest and latest departure time for the bus from New York City to San Ysidro?
The earliest bus departs from New York City to San Ysidro at 1:35am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from New York City to San Ysidro?
A bus trip from New York City to San Ysidro generates an estimated 98 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from New York City to San Ysidro, CA was searched and found on Dec 3, 2025 with a price of $306To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New York City to San Ysidro, CA, as early as possible.
You can expect to pay from $306 to $803 for a bus ticket from New York City to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $306 which is on 2025-12-03.
Top traveled bus routes
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Popular bus departures from New York City
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