Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Bus Station | CheapestFastest | ||||
 | Bus | Orlando Bus Station | Bus Station | No tags |
Last refresh of the prices: Last Monday at 10:13 PM EST.
Get from Orlando to Myrtle Beach
The journey takes about 18 hours 40 minutes and with fares starting at just $108, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Myrtle Beach?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Orlando Myrtle Beach recent customer reviews
Poor seating, bus from Orlando had weird odour
Shaniqueica G.
Frequently asked questions about traveling from Orlando to Myrtle Beach by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Myrtle Beach was searched and found on Nov 23, 2025 with a price of $126To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Myrtle Beach, as early as possible.
You can expect to pay from $126 to $171 for a bus ticket from Orlando to Myrtle Beach based on the last 2 days. You can expect to find the cheapest price for the trip at $126 which is on 2025-11-23.
