- Panama City to San Diego buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Panama City Beach Station | Balboa Park | No tags | ||||
![]() | Bus | Panama City Beach Station | Greyhound Bus Stop | No tags | ||||
FlixBus + Greyhound | Bus | Panama City Beach Station | Downtown SD (Seaport) | No tags | ||||
Greyhound + FlixBus | Bus | Panama City Beach Station | San Diego (Old Town-FlixBus) | No tags | ||||
Greyhound + FlixBus | Bus | Panama City Beach Station | UCSD Health La Jolla Station | No tags |
Get from Panama City to San Diego
The journey takes about 2 days, 11 hours 35 minutes and with fares starting at just $237, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and San Diego?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Panama City, US to San Diego, CA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panama City to San Diego?
The cheapest bus tickets from Panama City to San Diego start from $237. The average price for this route is around $238. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to San Diego?
The average bus trip duration from Panama City to San Diego is 2d 11h, covering a distance of 1850 miles (2984 km). The quickest bus can get you there in 2d 11h and is operated by Greyhound.
Which bus companies service the Panama City to San Diego route?
Several major bus companies operate on this route with 6 buses available per day.
What is the earliest and latest departure time for the bus from Panama City to San Diego?
The earliest bus departs from Panama City to San Diego at 2:15pm. And the latest bus departs at 9:10pm.
What are the CO₂ emissions for the bus trip from Panama City to San Diego?
A bus trip from Panama City to San Diego generates an estimated 75 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






