What is the travel distance from Pittsburgh to St. Louis?

The distance separating Pittsburgh and St. Louis is 557 miles (899 km).

What are the departure and arrival stations when taking the bus from Pittsburgh to St. Louis?

The majority of buses traveling from Pittsburgh to St. Louis start their journey at Intermodal Station and wind up at Gateway Station. These are the most popular departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in St. Louis?

Once in St. Louis, you can start exploring the city and discover its surroundings. The top sights and things to do are Missouri Botanical Garden, Municipal Theatre Association, Gateway Arch, Scott Joplin House State Historic Site and Citygarden Sculpture Park.

Bus Pittsburgh to St. Louis from $55 | Refundable Tickets

Next bus departures

Next departures for Pittsburgh to St. Louis on November 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	6:30pm	Pittsburgh Intermodal Station	12h 55m	6:25am	Gateway Station	CheapestFastest
Bus	10:50am	Pittsburgh Intermodal Station	13h 35m	11:25pm	Gateway Station	No tags
Bus	7:45pm	Pittsburgh Intermodal Station	21h	3:45pm	Gateway Station	No tags

Last refresh of the prices: Yesterday at 6:12 PM EST.

Compare 2 ways to go from Pittsburgh to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 13 hours 35 minutes and with fares starting at just $62, it presents an excellent value for a comfortable ride.

3bus per day

13h 35mAverage Duration

557 milesDistance

22kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$62 - $234	Average Duration13h 35m	CO₂ emissions 22kg CO₂e
Train	Average Price$80 - $1,250	Average Duration23h 24m	CO₂ emissions 82kg CO₂e

Where are the popular stops in Pittsburgh and St. Louis?

Stops in Pittsburgh

A
Intermodal Station
55 11th St, Pittsburgh, PA 15222, USA
Visit page
B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

Greyhound

3.5/587,396 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,446 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Pittsburgh to St. Louis by bus

What is the travel distance from Pittsburgh to St. Louis?
What are the departure and arrival stations when taking the bus from Pittsburgh to St. Louis?
What are the best sights and things to do in St. Louis?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/24

$90

11/25

$161

Today

$96

11/27

$73

11/28

No data

11/29

$82

11/30

$77

12/01

$61

The cheapest trip from Pittsburgh to St. Louis was searched and found on Dec 1, 2025 with a price of $61

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to St. Louis, as early as possible.

You can expect to pay from $61 to $229 for a bus ticket from Pittsburgh to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $61 which is on 2025-12-01.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.