Bus Tickets from Salisbury, NC to Chicago, IL

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TodayMay 18
TomorrowMay 19
from $176
TueMay 20
WedMay 21
ThuMay 22
FriMay 23
SatMay 24
SunMay 25

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 19 at
    Departure city: Salisbury
    Departure location: Salisbury (Citgo Fast Stop)
    Arrival time: May 20 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 19 at
    Departure city: Salisbury
    Departure location: Salisbury (Citgo Fast Stop)
    Arrival time: May 20 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 19 at
    Departure city: Salisbury
    Departure location: Salisbury (Citgo Fast Stop)
    Arrival time: May 20 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 19 at
    Departure city: Salisbury
    Departure location: Salisbury (Citgo Fast Stop)
    Arrival time: May 20 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 19 at
    Departure city: Salisbury
    Departure location: Salisbury (Citgo Fast Stop)
    Arrival time: May 20 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Salisbury to Chicago.

Bus
Average Price$137 - $270Average Duration1d 2h
23kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$242 - $363Average Duration1d 3h
85kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Salisbury to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 2 hours and with fares starting at just $137, it presents an excellent value for a comfortable ride.

6bus per day
1d 2hAverage Duration
$137Cheapest ticket
23kgCO₂ emissions

Bus Salisbury to Chicago: Trip Overview

Average ticket price$197
Average bus trip duration1d 2h
Number of daily buses6
Earliest bus departure12:25pm
Distance576 miles (929 km)
Latest bus departure7:10pm

Salisbury to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Salisbury to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Salisbury to Chicago.

Discover how much the bus trip from Salisbury to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Salisbury - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/16
No data
05/17
No data
Today
No data
05/19
$187
05/20
No data
05/21
No data
05/22
$137
05/23
No data
busbud logoThe cheapest trip from Salisbury to Chicago was searched and found on May 22, 2025 with a price of $137

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury to Chicago, as early as possible.

You can expect to pay from $137 to $210 for a bus ticket from Salisbury to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $137 which is on 2025-05-22.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Salisbury to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Salisbury to Chicago.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Salisbury to Chicago will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Salisbury to Chicago while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Salisbury to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Salisbury by bus?

Bus from Salisbury to Chicago

You can also go to Chicago by train

Train from Salisbury to Chicago

Why choose Busbud?

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