Bus from St. Louis to Chicago: Tickets & Schedules
Search form
Next available departures
Next departures for St. Louis to Chicago on September 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
CheapestFastest
Wifi
Toilet
Power outlets
Gateway Station
Chicago (Union Station), IL
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Wifi
Toilet
Power outlets
Gateway Station
537-517 W. Jackson Blvd
No tags
FlixBus + Greyhound Lines, Inc.
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
No tags
Next departures for St. Louis to Chicago on September 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
CheapestFastest
Wifi
Toilet
Power outlets
Gateway Station
Chicago (Union Station), IL
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Wifi
Toilet
Power outlets
Gateway Station
537-517 W. Jackson Blvd
No tags
FlixBus + Greyhound Lines, Inc.
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
No tags
Wifi
Toilet
Power outlets
Gateway Station
Chicago (Union Station), IL
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Next departures for St. Louis to Chicago on September 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
CheapestFastest
Wifi
Toilet
Power outlets
Gateway Station
Chicago (Union Station), IL
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Wifi
Toilet
Power outlets
Gateway Station
537-517 W. Jackson Blvd
No tags
FlixBus + Greyhound Lines, Inc.
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
No tags
Wifi
Toilet
Power outlets
Gateway Station
Chicago (Union Station), IL
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Next departures for St. Louis to Chicago on September 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
Cheapest
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
Fastest
Wifi
Toilet
Power outlets
Gateway Station
Chicago (Union Station), IL
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Wifi
Toilet
Power outlets
Gateway Station
537-517 W. Jackson Blvd
No tags
FlixBus + Greyhound Lines, Inc.
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
No tags
Wifi
Toilet
Power outlets
Gateway Station
Chicago (Union Station), IL
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Next departures for St. Louis to Chicago on September 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
CheapestFastest
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Wifi
Toilet
Power outlets
Gateway Station
537-517 W. Jackson Blvd
No tags
FlixBus + Greyhound Lines, Inc.
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
No tags
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
No tags
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
No tags
Next departures for St. Louis to Chicago on September 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
CheapestFastest
Wifi
Toilet
Power outlets
Gateway Station
Chicago (Union Station), IL
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
No tags
Wifi
Toilet
Power outlets
Gateway Station
Chicago (Union Station), IL
No tags
Wifi
Toilet
Power outlets
Gateway Station
537-517 W. Jackson Blvd
No tags
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
No tags
Next departures for St. Louis to Chicago on September 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
CheapestFastest
Wifi
Toilet
Power outlets
Gateway Station
Chicago (Union Station), IL
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Wifi
Toilet
Power outlets
Gateway Station
Chicago 95Th & Dan Ryan
No tags
Wifi
Toilet
Power outlets
Gateway Station
Chicago (Union Station), IL
No tags
Wifi
Toilet
Power outlets
Gateway Station
Downtown Greyhound Station
No tags
Wifi
Toilet
Power outlets
Gateway Station
537-517 W. Jackson Blvd
No tags
Last refresh of the prices: Today at 9:02 PM CDT.
Compare 2 ways to go from St. Louis to Chicago
We recommend taking the train
Among the sustainable travel choices, the Train stands out as a good way to reach Chicago. The journey takes about 5 hours 5 minutes and with fares starting at just DKK 195, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
FlixBus St. Louis Chicago recent customer reviews
I found the employees very professional , especially the bus driver
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound St. Louis Chicago recent customer reviews
My trip was changed then cancelled and the next bus took 2 hrs . My connection to complete my trip made me arrive at my final destination at 4 am to an empty station where I couldn't get any assistance. Couldn't get a taxi at that hour there. It was a very horrible experience.
1.0 out of 5 stars
Raydell W.
My first time from along time to many stops little confusing if we were close or what time we really will be in Chicago in all Ok!
3.0 out of 5 stars
Shelia S.
Very professional and courteous. Actually, quite a bit more professional and less stressful than air travel presently. Pleasantly surprised!
Users have shared positive experiences about the train service, highlighting its punctuality, comfort, and friendly conductors. Many found it to be a convenient mode of travel for this distance. However, there were observations regarding inconsistent interactions from staff with passengers of different backgrounds during ticket checks and arrivals.
Amtrak St. Louis Chicago recent customer reviews
Smooth ride. The man who did our tickets from St. Louis we noticed after checking white people's tickets he said thanks and have a great day. To black people he said nothing. Then upon arriving in Chicago that man offered no one a hand down or said goodbye.
4.0 out of 5 stars
Yvonne H.
Fabulous! Train is the way to go for this distance!! On time, comfortable, friendly conductors, and SO convenient!
5.0 out of 5 stars
Kendra H.
Great have not rode a train in about 40 years. It was very enjoyable.
Based on 20 reviews, the company was rated 4.2 stars on Busbud. Travelers were especially satisfied with the staff and the timeliness but often complained with the ticket access. Burlington Trailways ticket prices on this trip start at DKK 1,249
Frequently asked questions about traveling from St. Louis to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from St. Louis to Chicago?
The cheapest bus tickets from St. Louis to Chicago start from DKK 269. The average price for this route is around DKK 342. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Chicago?
The average bus trip duration from St. Louis to Chicago is 8h 25m, covering a distance of 257 miles (415 km). The quickest bus can get you there in 4h 40m and is operated by FlixBus.
Which bus companies service the St. Louis to Chicago route?
What is the earliest and latest departure time for the bus from St. Louis to Chicago?
The earliest bus departs from St. Louis to Chicago at 2:00am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to Chicago?
A bus trip from St. Louis to Chicago generates an estimated 10.362775000000001 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from St. Louis to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.
Which bus company has the best Wi-Fi from St. Louis to Chicago?
Based on reviews on Busbud, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.
Which bus company has the most timely service from St. Louis to Chicago?
According to Busbud traveler reviews, the most timely bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Chicago?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
09/14
DKK 328
09/15
DKK 649
Today
DKK 723
09/17
DKK 522
09/18
DKK 301
09/19
DKK 275
09/20
DKK 288
09/21
DKK 248
The cheapest trip from St. Louis to Chicago was searched and found on Sep 21, 2026 with a price of DKK 248
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Chicago, as early as possible.
You can expect to pay from DKK 248 to DKK 1,806 for a bus ticket from St. Louis to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at DKK 248 which is on 2026-09-21.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from St. Louis to Chicago was searched and found on Sep 21, 2026 with a price of DKK 248
