Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Based on 33 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the departure location and the staff but often complained with the wifi. Valley Transit ticket prices on this trip start at $86
Frequently asked questions about traveling from San Antonio, US to Midland, TX, US by bus
What is the distance between San Antonio and Midland?
The distance separating San Antonio and Midland is 278 miles (447 km).
What are the departure and arrival stations when taking the bus from San Antonio to Midland?
If you're headed to Midland from San Antonio, chances are that your bus will leave from San Antonio Bus Station and arrive at Midland Bus Stop. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
$247
11/19
$263
Today
$135
11/21
$279
11/22
$264
11/23
No data
11/24
$196
11/25
$172
The cheapest trip from San Antonio, US to Midland, TX, US was searched and found on Nov 20, 2025 with a price of $135
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Midland, TX, US, as early as possible.
You can expect to pay from $135 to $279 for a bus ticket from San Antonio, US to Midland, TX, US based on the last 2 days. You can expect to find the cheapest price for the trip at $172 which is on 2025-11-25.
The cheapest trip from San Antonio, US to Midland, TX, US was searched and found on Nov 20, 2025 with a price of $135
