Compare 2 ways to go from San Diego to Charleston.
Busbud recommends taking the bus from San Diego to CharlestonAmong the sustainable travel choices, the bus stands out as the good way to reach Charleston. The journey takes about 2 days, 12 hours 25 minutes and with fares starting at just $243, it presents an excellent value for a comfortable ride.
Bus San Diego to Charleston: Trip Overview
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San Diego to Charleston Bus
Busbud helps you find a bus from San Diego to Charleston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from San Diego to Charleston will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Charleston from San Diego, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in San Diego and Charleston?
Frequently asked questions for your trip San Diego - Charleston
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego to Charleston was searched and found on May 9, 2025 with a price of $350To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Charleston, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and Charleston!
Much more than a mere vehicle taking you from San Diego to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to Charleston.
Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to Charleston while indulging in miles on end of beautiful scenic views.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
What's the cheapest way to go from San Diego to Charleston?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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