Bus Tickets from San Diego, CA, US to Irvine, US

Previously seen trips

Next departures for San Diego to Irvine on November 19
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakBus
Santa Fe Depot
Irvine StationNo tags
AmtrakBus
Santa Fe Depot
Irvine StationNo tags
AmtrakBus
Santa Fe Depot
Irvine StationNo tags
AmtrakBus
Santa Fe Depot
Irvine StationNo tags
AmtrakBus
Santa Fe Depot
Irvine StationNo tags

Compare 2 ways to go from San Diego to Irvine

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Irvine. The journey takes about 1 hour 45 minutes and with fares starting at just $14, it presents an excellent value for a comfortable ride.

1bus per day
1h 45mAverage Duration
73 milesDistance
3kgCO₂ emissions
Average Price$14 - $14Average Duration1h 45m
3kg CO₂e
Average Price$29 - $30Average Duration1h 47m
11kg CO₂e

Frequently asked questions about traveling from San Diego, CA, US to Irvine, US by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/17
$27
11/18
$27
Today
No data
11/20
No data
11/21
No data
11/22
No data
11/23
No data
11/24
No data
busbud logoThe cheapest trip from San Diego, CA, US to Irvine, US was searched and found on Nov 17, 2025 with a price of $27

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Irvine, US, as early as possible.

What's the cheapest way to go from San Diego, CA, US to Irvine, US?

busbud logoThe bus is the cheapest travel choice for this destination

People from around the world trust Busbud