Bus Tickets from San Luis Obispo to Irvine, US

Previously seen trips

Next departures for San Luis Obispo to Irvine on November 25
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakBus
Cal Poly Vista Grande Dining Complex
Irvine StationNo tags
AmtrakBus
AMTRAK Station
Irvine StationNo tags
AmtrakBus
Cal Poly Vista Grande Dining Complex
Irvine StationNo tags
AmtrakBus
AMTRAK Station
Irvine StationNo tags
AmtrakBus
Cal Poly Vista Grande Dining Complex
Irvine StationNo tags

Compare 2 ways to go from San Luis Obispo to Irvine

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Irvine. The journey takes about 7 hours and with fares starting at just $51, it presents an excellent value for a comfortable ride.

3train per day
7hAverage Duration
201 milesDistance
29kgCO₂ emissions
Average Price$76 - $80Average Duration8h 35m
8kg CO₂e
Average Price$51 - $112Average Duration7h
29kg CO₂e

Frequently asked questions about traveling from San Luis Obispo to Irvine, US by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/22
$55
11/23
$55
Today
$55
11/25
$55
11/26
$55
11/27
$55
11/28
$55
11/29
$55
busbud logoThe cheapest trip from San Luis Obispo to Irvine, US was searched and found on Nov 22, 2025 with a price of $55

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to Irvine, US, as early as possible.

You can expect to pay from $55 to $91 for a bus ticket from San Luis Obispo to Irvine, US based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2025-11-25.

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