Next departures to San Francisco
One passenger / one way
- This trip is recommended because it is: CheapestDeparture time: August 2 atDeparture city: San Luis ObispoDeparture location: AMTRAK StationArrival time: August 2 atDestination city: San FranciscoDestination location: Mission St & Fremont StOperated by: Amtrak
Vehicle: BusDuration: - This trip is recommended because it is: FastestDeparture time: August 2 atDeparture city: San Luis ObispoDeparture location: San Luis ObispoArrival time: August 2 atDestination city: San FranciscoDestination location: 409 Townsend St, SFOperated by: FlixBus
Vehicle: BusDuration: - Departure time: August 2 atDeparture city: San Luis ObispoDeparture location: San Luis ObispoArrival time: August 2 atDestination city: San FranciscoDestination location: 409 Townsend St, SFOperated by: FlixBusVehicle: BusDuration:
- Departure time: August 2 atDeparture city: San Luis ObispoDeparture location: Cal Poly Vista Grande Dining ComplexArrival time: August 2 atDestination city: San FranciscoDestination location: Mission St & Fremont StOperated by: AmtrakVehicle: BusDuration:
- Departure time: August 2 atDeparture city: San Luis ObispoDeparture location: AMTRAK StationArrival time: August 2 atDestination city: San FranciscoDestination location: Mission St & Fremont StOperated by: AmtrakVehicle: BusDuration:
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Compare 2 ways to go from San Luis Obispo to San Francisco.
Busbud recommends taking the bus from San Luis Obispo to San FranciscoAmong the sustainable travel choices, the bus stands out as the good way to reach San Francisco. The journey takes about 4 hours 40 minutes and with fares starting at just $16, it presents an excellent value for a comfortable ride.
Bus San Luis Obispo to San Francisco, US: Trip Overview
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San Luis Obispo to San Francisco Bus
With Busbud, comparing and booking tickets for a bus from San Luis Obispo to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from San Luis Obispo to San Francisco from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from San Luis Obispo to San Francisco, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in San Luis Obispo and San Francisco?
Frequently asked questions for your trip San Luis Obispo - San Francisco, US
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Luis Obispo to San Francisco, US was searched and found on Aug 1, 2025 with a price of $14To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to San Francisco, US, as early as possible.
You can expect to pay from $14 to $89 for a bus ticket from San Luis Obispo to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at $14 which is on 2025-08-02.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from San Luis Obispo to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Luis Obispo to San Francisco, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Luis Obispo to San Francisco that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from San Luis Obispo to San Francisco, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
What's the cheapest way to go from San Luis Obispo to San Francisco, US?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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