Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rodoviária de Santa Cruz do Sul | Rodoviária do Tietê | CheapestFastest |
Last refresh of the prices: Yesterday at 11:32 PM -03.
Get from Santa Cruz do Sul to São Paulo
The journey takes about 22 hours 40 minutes and with fares starting at just $67, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santa Cruz do Sul and São Paulo?
Stops in Santa Cruz do Sul
- A
Rodoviária de Santa Cruz do Sul
Tv. Érico Veríssimo, 400 - Vila Schulz, Santa Cruz do Sul - RS, Brazil
Stops in São Paulo
- ATerminal Rodoviário da Barra Funda, Avenida Auro Soares de Moura Andrade, 664 - Barra Funda, São Paulo - SP, 01156-001, Brazil
- CTerminal Intermunicipal do Jabaquara, Rua dos Jequitibás, 80 - Jabaquara, São Paulo - SP, 04321-090
- D
Praça do Patriarca
Praça do Patriarca 78, Centro, São Paulo - SP, Brazil - E
São Paulo
São Paulo - F
Tietê
Terminal Rodoviário do Tietê, Avenida Cruzeiro do Sul, , 1800 Santana , 02030-000 São Paulo, SP
Compare bus companies
Based on 482 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the departure location and the ticket access but often complained with the wifi. Viação Penha ticket prices on this trip start at $67
Frequently asked questions about traveling from Santa Cruz do Sul to São Paulo by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Cruz do Sul to São Paulo was searched and found on Nov 26, 2025 with a price of $55To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Cruz do Sul to São Paulo, as early as possible.
You can expect to pay from $55 to $60 for a bus ticket from Santa Cruz do Sul to São Paulo based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2025-11-26.
