Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal de Ómnibus | Cheapest | ||||
| Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal de Ómnibus | Fastest | ||||
| Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal de Ómnibus | No tags | ||||
 | Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal de Ómnibus | No tags | ||||
| Bus | Estación Terminal de Ómnibius, Santa Fe | Terminal de Ómnibus | No tags |
Last refresh of the prices: Last Friday at 1:54 PM -03.
Get from Santa Fe to Puerto Iguazú
The journey takes about 16 hours 15 minutes and with fares starting at just $62, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santa Fe and Puerto Iguazú?
Stops in Santa Fe
- A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
Stops in Puerto Iguazú
- AAv. Misiónes 1-99, N3370FBA Puerto Iguazú, Misiónes, Argentina
- B
Puerto Iguazú Accesso
RN12, Puerto Iguazú, Misiónes, Argentina
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Frequently asked questions about traveling from Santa Fe, AR to Puerto Iguazú by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santa Fe to Puerto Iguazú?
The cheapest bus tickets from Santa Fe to Puerto Iguazú start from $62. The average price for this route is around $94. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santa Fe to Puerto Iguazú?
The average bus trip duration from Santa Fe to Puerto Iguazú is 16h 15m, covering a distance of 558 miles (900 km). The quickest bus can get you there in 14h 25m and is operated by Rio Uruguay.
Which bus companies service the Santa Fe to Puerto Iguazú route?
Several major bus companies operate on this route with 4 buses available per day, including services from Rio Uruguay, 20 de Junio, Expreso Singer.
What is the earliest and latest departure time for the bus from Santa Fe to Puerto Iguazú?
The earliest bus departs from Santa Fe to Puerto Iguazú at 12:15am. And the latest bus departs at 10:20pm.
What are the CO₂ emissions for the bus trip from Santa Fe to Puerto Iguazú?
A bus trip from Santa Fe to Puerto Iguazú generates an estimated 22 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Santa Fe to Puerto Iguazú?
According to Busbud customers, the highest-rated bus company on this route is 20 de Junio, with an average rating of 4.0 out of 5 stars based on 588 reviews.
Which bus company has the best Wi-Fi from Santa Fe to Puerto Iguazú?
Based on reviews on Busbud, the bus company 20 de Junio has the best Wi-Fi rating with a score of 2.3.
Which bus company has the most timely service from Santa Fe to Puerto Iguazú?
According to Busbud traveller reviews, the most timely bus company on this route is 20 de Junio, with a punctuality rating of 4.1 out of 5 stars.
Which bus company has the cleanest buses from Santa Fe to Puerto Iguazú?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is 20 de Junio, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Fe, AR to Puerto Iguazú was searched and found on Dec 26, 2025 with a price of $79To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe, AR to Puerto Iguazú, as early as possible.
You can expect to pay from $79 to $114 for a bus ticket from Santa Fe, AR to Puerto Iguazú based on the last 2 days. You can expect to find the cheapest price for the trip at $79 which is on 2025-12-26.
