Bus Tickets from Santiago, CL to Melipeuco

Find affordable bus tickets from Santiago, CL to Melipeuco with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
MonJun 2
from $16
TueJun 3
WedJun 4
ThuJun 5
from $18
FriJun 6
SatJun 7
SunJun 8
MonJun 9

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 5 at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: June 6 at
    Destination city: Melipeuco
    Destination location: Melipeuco
    Operated by: Nar Bus InternacionalNar Bus Internacional
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 5 at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: June 6 at
    Destination city: Melipeuco
    Destination location: Melipeuco
    Operated by: Buses TranSantinBuses TranSantin
    Vehicle: BusDuration:
  • Departure time: June 5 at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: June 6 at
    Destination city: Melipeuco
    Destination location: Melipeuco
    Operated by: Nar Bus InternacionalNar Bus Internacional
    Vehicle: BusDuration:
  • Departure time: June 5 at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: June 6 at
    Destination city: Melipeuco
    Destination location: Melipeuco
    Operated by: Buses TranSantinBuses TranSantin
    Vehicle: BusDuration:
  • Departure time: June 5 at
    Departure city: Santiago
    Departure location: Terminal Sur
    Arrival time: June 6 at
    Destination city: Melipeuco
    Destination location: Melipeuco
    Operated by: Nar Bus InternacionalNar Bus Internacional
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Santiago to Melipeuco: Trip Overview

Average ticket price$17
Average bus trip duration10h
Number of daily buses3
Earliest bus departure10:00pm
Distance377 miles (607 km)
Latest bus departure10:45pm

Santiago to Melipeuco Bus

With Busbud, comparing and booking tickets for a bus from Santiago to Melipeuco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Santiago to Melipeuco from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Santiago to Melipeuco, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Santiago, CL - Melipeuco

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/29
$17
05/30
No data
Today
No data
06/01
$19
06/02
$15
06/03
No data
06/04
$12
06/05
$17
busbud logoThe cheapest trip from Santiago to Melipeuco was searched and found on Jun 4, 2025 with a price of $12

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago to Melipeuco, as early as possible.

You can expect to pay from $12 to $19 for a bus ticket from Santiago to Melipeuco based on the last 2 days. You can expect to find the cheapest price for the trip at $12 which is on 2025-06-04.

Usually Buses TranSantin, Narbus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Santiago to Melipeuco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santiago to Melipeuco, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santiago to Melipeuco that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santiago to Melipeuco.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Santiago by bus?

Bus from Santiago to Melipeuco

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Santiago

Buses Leaving from Santiago

Buses Going to Santiago

Popular Buses Connecting Melipeuco

Buses Leaving from Melipeuco

Buses Going to Melipeuco