Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Waterloo (Union Bus Depot) | Downtown Greyhound Station | CheapestFastest | ||||
| Bus | Waterloo (Union Bus Depot) | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Yesterday at 11:05 AM CST.
Get from Waterloo to Chicago
The journey takes about 7 hours 20 minutes and with fares starting at just $50, it presents an excellent value for a comfortable ride.
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Frequently asked questions about traveling from Waterloo, IA, US to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Waterloo to Chicago?
The cheapest bus tickets from Waterloo to Chicago start from $50. The average price for this route is around $64. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Waterloo to Chicago?
The average bus trip duration from Waterloo to Chicago is 7h 20m, covering a distance of 247 miles (399 km). The quickest bus can get you there in 6h 30m and is operated by Burlington Trailways.
Which bus companies service the Waterloo to Chicago route?
Several major bus companies operate on this route with 2 buses available per day, including services from Greyhound, Burlington Trailways.
What is the earliest and latest departure time for the bus from Waterloo to Chicago?
The earliest bus departs from Waterloo to Chicago at 12:15pm. And the latest bus departs at 12:15pm.
What are the CO₂ emissions for the bus trip from Waterloo to Chicago?
A bus trip from Waterloo to Chicago generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Waterloo to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.
Which bus company has the best Wi-Fi from Waterloo to Chicago?
Based on reviews on Busbud, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.
Which bus company has the most timely service from Waterloo to Chicago?
According to Busbud traveller reviews, the most timely bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Waterloo to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Waterloo, IA, US to Chicago was searched and found on Jan 12, 2026 with a price of $46To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Waterloo, IA, US to Chicago, as early as possible.
You can expect to pay from $46 to $49 for a bus ticket from Waterloo, IA, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $46 which is on 2026-01-12.
