Bus Tickets from Buffalo, NY to St. Louis

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Compare 2 ways to go from Buffalo to St. Louis

Bus
Average PriceUS$116 - US$222Average Duration1d 8h
27kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$196 - US$781Average Duration19h 28m
98kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Buffalo to St. Louis

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 19 hours 28 minutes, and with fares starting at just US$196, it presents an excellent value for a comfortable ride.

1train per day
19h 28mAverage Duration
US$196Cheapest ticket
98kgCO₂ emissions

Bus Buffalo, NY to St. Louis: Trip Overview

Average Ticket PriceUS$162
Average Bus Trip Duration1d 8h
Number of daily buses5
Earliest bus departure7:55am
Distance1077 km
Latest bus departure11:20pm

Buffalo to St. Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Buffalo to St. Louis.

We make it our job to connect you with the most dependable bus companies that cover bus service from Buffalo to St. Louis.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Buffalo, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Buffalo, NY - St. Louis

  1. What is the travel distance from Buffalo to St. Louis?

    It's about 1065 km (660 miles) from Buffalo to St. Louis.

  2. What are the departure and arrival locations for buses traveling from Buffalo to St. Louis?

    Buses departing from Buffalo Airport in Buffalo will take you to Gateway Station in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-27
US$124
07-28
No data
Today
No data
07-30
No data
07-31
US$75
08-01
US$96
08-02
No data
08-03
No data
busbud logoThe cheapest trip from Buffalo, NY to St. Louis was searched and found on Jul 31, 2025 with a price of US$75

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to St. Louis, as early as possible.

You can expect to pay from US$75 to US$124 for a bus ticket from Buffalo, NY to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$75 which is on 2025-07-31.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Buffalo to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Buffalo to St. Louis.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Buffalo to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Buffalo to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Buffalo, NY to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Buffalo, NY by bus?

Bus from Buffalo, NY to St. Louis

You can also go to St. Louis by train

Train from Buffalo, NY to St. Louis

Why choose Busbud?

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