What is the distance between Charleston and Tampa?

The distance between Charleston and Tampa is approximately 591 km (366 miles).

What are the departure and arrival locations for buses traveling from Charleston to Tampa?

Buses departing from Charleston Bus Station in Charleston will take you to Tampa 13th Avenue Bus Stop (McDonald's) in Tampa.

Bus Charleston to Tampa from $89 | Refundable Tickets

Next bus departures

Next departures for Charleston to Tampa on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	11:15am	4565 Gaynor Ave, North Charleston	18h 45m	6:00am	Tampa Bus Station	CheapestFastest

Next departures for Charleston to Tampa on November 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	11:15am	4565 Gaynor Ave, North Charleston	18h 45m	6:00am	Tampa Bus Station	CheapestFastest

Next departures for Charleston to Tampa on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	11:15am	4565 Gaynor Ave, North Charleston	18h 45m	6:00am	Tampa Bus Station	CheapestFastest

Last refresh of the prices: Yesterday at 10:35 AM EST.

Compare 2 ways to go from Charleston to Tampa

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Tampa. The journey takes about 16 hours 50 minutes, and with fares starting at just $104, it presents an excellent value for a comfortable ride.

1train per day

16h 50mAverage Duration

596 kmDistance

54kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$109 - $257	Average Duration18h 45m	CO₂ emissions 15kg CO₂e
Train	Average Price$104 - $751	Average Duration16h 50m	CO₂ emissions 54kg CO₂e

Where are the popular stops in Charleston and Tampa?

Stops in Charleston

A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405

Stops in Tampa

A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605
B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA
C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA
D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA
E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA
F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA

Compare bus companies

FlixBus

3.5/511,440 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Greyhound

3.5/587,394 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Charleston, SC, US to Tampa by bus

What is the distance between Charleston and Tampa?
The distance between Charleston and Tampa is approximately 591 km (366 miles).
What are the departure and arrival locations for buses traveling from Charleston to Tampa?
Buses departing from Charleston Bus Station in Charleston will take you to Tampa 13th Avenue Bus Stop (McDonald's) in Tampa.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-23

No data

11-24

$110

Today

No data

11-26

$136

11-27

$145

11-28

No data

11-29

$154

11-30

No data

The cheapest trip from Charleston, SC, US to Tampa was searched and found on Nov 24, 2025 with a price of $110

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Tampa, as early as possible.

You can expect to pay from $110 to $154 for a bus ticket from Charleston, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $136 which is on 2025-11-26.