Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | 4565 Gaynor Ave, North Charleston | Tampa Bus Station | CheapestFastest |
Last refresh of the prices: Today at 10:01 AM EST.
Compare 2 ways to go from Charleston to Tampa
Among the sustainable travel choices, the train stands out as a good way to reach Tampa. The journey takes about 16 hours 50 minutes, and with fares starting at just $103, it presents an excellent value for a comfortable ride.
Where are the popular stops in Charleston and Tampa?
Stops in Charleston
- A
Charleston Bus Station
3610 Dorchester Rd, North Charleston, SC 29405
Stops in Tampa
- A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605 - B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA - C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA - D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA - E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA - F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Compare bus companies
Frequently asked questions about travelling from Charleston, SC, US to Tampa by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Charleston to Tampa?
The cheapest bus tickets from Charleston to Tampa start from $107. The average price for this route is around $147. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Charleston to Tampa?
The average bus travel time from Charleston to Tampa is 18h 45m, covering a distance of 596 km. The quickest bus can get you there in 14h 45m and is operated by FlixBus.
Which bus companies service the Charleston to Tampa route?
What are the earliest and latest departure times for the bus from Charleston to Tampa?
The earliest bus departs from Charleston to Tampa at 11:15am. And the latest bus departs at 3:15pm.
What are the CO₂ emissions for the bus trip from Charleston to Tampa?
A bus trip from Charleston to Tampa generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Charleston to Tampa?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from Charleston to Tampa?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Charleston to Tampa?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Charleston to Tampa?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charleston, SC, US to Tampa was searched and found on Nov 26, 2025 with a price of $135To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Tampa, as early as possible.
You can expect to pay from $135 to $152 for a bus ticket from Charleston, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $152 which is on 2025-11-29.
What's the cheapest way to go from Charleston, SC, US to Tampa?
The bus is the cheapest travel choice for this destination
