Next departures for Charleston to Tampa on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
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Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Tampa Bus Station
CheapestFastest
Next departures for Charleston to Tampa on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Tampa Bus Station
CheapestFastest
Next departures for Charleston to Tampa on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Tampa Bus Station
CheapestFastest
Last refresh of the prices: Today at 9:17 AM EST.
Compare 2 ways to go from Charleston to Tampa
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Tampa. The journey takes about 16 hours 50 minutes and with fares starting at just $72, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Charleston, SC, US to Tampa by bus
What is the distance between Charleston and Tampa?
Charleston and Tampa are 366 miles (591 km) apart.
What are the departure and arrival stations when taking the bus from Charleston to Tampa?
If you're headed to Tampa from Charleston, chances are that your bus will depart from Charleston Bus Station and arrive at Tampa 13th Avenue Bus Stop (McDonald's). These are the main pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/21
$81
11/22
$100
Today
No data
11/24
$76
11/25
No data
11/26
$94
11/27
$100
11/28
No data
The cheapest trip from Charleston, SC, US to Tampa was searched and found on Nov 24, 2025 with a price of $76
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Tampa, as early as possible.
You can expect to pay from $76 to $100 for a bus ticket from Charleston, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $76 which is on 2025-11-24.
What's the cheapest way to go from Charleston, SC, US to Tampa?
The bus is the cheapest travel choice for this destination
The cheapest trip from Charleston, SC, US to Tampa was searched and found on Nov 24, 2025 with a price of $76
The bus is the cheapest travel choice for this destination
