Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | BILOXI | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Chicago 95Th & Dan Ryan | BILOXI | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | BILOXI | No tags | ||||
 | Bus | 537-517 W. Jackson Blvd | BILOXI | No tags | ||||
Tornado Bus + Expreso | Bus | Chicago, IL | Love's | No tags |
Last refresh of the prices: Today at 1:29 AM CST.
Get from Chicago to Biloxi
The journey takes about 1 day, 5 hours 15 minutes, and with fares starting at just $175, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Biloxi?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Stops in Biloxi
- A11332 Cedar Lake Rd, Biloxi, MS 39532, USA
- B
Transit Center
820 Dr Martin Luther King Jr Blvd, Biloxi, MS 39530, USA
Compare bus companies
Frequently asked questions about travelling from Chicago to Biloxi by bus
What is the travel distance from Chicago to Biloxi?
The distance covered from Chicago to Biloxi is 1280 km (794 miles).
What are the departure and arrival locations for buses traveling from Chicago to Biloxi?
Buses traveling this route start their trip at Downtown Greyhound Station, in Chicago, and end it at Love's, in Biloxi.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Biloxi was searched and found on Nov 23, 2025 with a price of $172To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Biloxi, as early as possible.
You can expect to pay from $172 to $477 for a bus ticket from Chicago to Biloxi based on the last 2 days. You can expect to find the cheapest price for the trip at $172 which is on 2025-11-23.
Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
