Bus Tickets from Chicago to Biloxi

Next bus departures

Next departures for Chicago to Biloxi on November 21
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
BILOXICheapest
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
BILOXIFastest
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
BILOXINo tags
Greyhound Lines, Inc.Bus
537-517 W. Jackson Blvd
BILOXINo tags
Tornado Bus + Expreso
Bus
Chicago, IL
Love'sNo tags

Last refresh of the prices: Today at 1:29 AM CST.

Get from Chicago to Biloxi

This route is served by bus only

The journey takes about 1 day, 5 hours 15 minutes and with fares starting at just $122, it presents an excellent value for a comfortable ride.

11bus per day
1d 5hAverage Duration
795 milesDistance
32kgCO₂ emissions

Frequently asked questions about traveling from Chicago to Biloxi by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/18
$177
11/19
$189
Today
No data
11/21
$257
11/22
No data
11/23
$119
11/24
No data
11/25
No data
busbud logoThe cheapest trip from Chicago to Biloxi was searched and found on Nov 23, 2025 with a price of $119

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Biloxi, as early as possible.

You can expect to pay from $119 to $330 for a bus ticket from Chicago to Biloxi based on the last 2 days. You can expect to find the cheapest price for the trip at $119 which is on 2025-11-23.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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