Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Amtrak Station | Old Town San Diego | CheapestFastest | |||||
Greyhound Lines, Inc. + FlixBus | Amtrak Station | San Diego (Old Town-FlixBus) | No tags | |||||
 | Amtrak Station | San Diego (Old Town-FlixBus) | No tags | |||||
 | Amtrak Station | Greyhound Bus Stop | No tags | |||||
| Amtrak Station | Old Town San Diego | No tags |
Last refresh of the prices: Last Monday at 9:21 AM PST.
Get from Fresno to San Diego
The journey takes about 9 hours 30 minutes, and with fares starting at just $69, it presents an excellent value for a comfortable ride.
Where are the popular stops in Fresno and San Diego?
Stops in Fresno
- A2660 Tulare St, Fresno, CA 93721, USA
- B1157 F St, Fresno, CA 93706 , USA
- C919 E St, Fresno, CA 93706, USA
- D
Train / Greyhound Station
1033 H St, Fresno, CA 93721 - E
W Shaw Ave
Carl's Jr., 5275 W Shaw Ave, Fresno, CA 93722, USA
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
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Frequently asked questions about travelling from Fresno, US to San Diego, CA, US by bus
How far is Fresno from San Diego?
The distance between Fresno and San Diego is approximately 508 km (315 miles).
What are the departure and arrival locations for buses traveling from Fresno to San Diego?
Buses departing from Amtrak Station in Fresno will take you to Mission Valley Sheraton in San Diego.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Fresno, US to San Diego, CA, US was searched and found on Nov 18, 2025 with a price of $71To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Fresno, US to San Diego, CA, US, as early as possible.
You can expect to pay from $71 to $240 for a bus ticket from Fresno, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $71 which is on 2025-11-22.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
