Bus from Houston, US to Greenville, SC: Tickets & Schedules
Next departures
Next departures for Houston to Greenville on December 5
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Houston Bus Station
1116 Woodruff Rd
Cheapest
Houston Lockwood, (TX - TBC Lockwood)
Greenville, (SC - Taqueria Guadalajara #3)
Fastest
Amtrak Station
Greenville Station
No tags
Houston Bus Station
1116 Woodruff Rd
No tags
FlixBus + Greyhound Lines, Inc.
Downtown Gray & Smith
1116 Woodruff Rd
No tags
Next departures for Houston to Greenville on December 6
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Downtown Gray & Smith
1116 Woodruff Rd
Cheapest
Houston Lockwood, (TX - TBC Lockwood)
Greenville, (SC - Taqueria Guadalajara #3)
Fastest
Houston Bus Station
1116 Woodruff Rd
No tags
Greyhound Lines, Inc. + FlixBus
Houston Bus Station
1116 Woodruff Rd
No tags
Valley Transit + Greyhound Lines, Inc. + FlixBus
Hillcroft Ave & Southwest Freeway
1116 Woodruff Rd
No tags
Next departures for Houston to Greenville on December 7
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Downtown Gray & Smith
1116 Woodruff Rd
Cheapest
Houston Lockwood, (TX - TBC Lockwood)
Greenville, (SC - Taqueria Guadalajara #3)
Fastest
Houston Bus Station
1116 Woodruff Rd
No tags
Greyhound Lines, Inc. + FlixBus
Houston Bus Station
1116 Woodruff Rd
No tags
Valley Transit + Greyhound Lines, Inc. + FlixBus
Hillcroft Ave & Southwest Freeway
1116 Woodruff Rd
No tags
Next departures for Houston to Greenville on December 8
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Houston Bus Station
1116 Woodruff Rd
Cheapest
Houston Lockwood, (TX - TBC Lockwood)
Greenville, (SC - Taqueria Guadalajara #3)
Fastest
Amtrak Station
Greenville Station
No tags
Houston Bus Station
1116 Woodruff Rd
No tags
Greyhound Lines, Inc. + FlixBus
Houston Bus Station
1116 Woodruff Rd
No tags
Next departures for Houston to Greenville on December 9
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines Mexico + Greyhound Lines, Inc.
Houston Uptown/Upper Kirby
1116 Woodruff Rd
Cheapest
Houston Lockwood, (TX - TBC Lockwood)
Greenville, (SC - Taqueria Guadalajara #3)
Fastest
Houston Bus Station
1116 Woodruff Rd
No tags
Greyhound Lines, Inc. + FlixBus
Houston Bus Station
1116 Woodruff Rd
No tags
Valley Transit + Greyhound Lines, Inc. + FlixBus
Hillcroft Ave & Southwest Freeway
1116 Woodruff Rd
No tags
Next departures for Houston to Greenville on December 10
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Downtown Gray & Smith
1116 Woodruff Rd
Cheapest
Houston Lockwood, (TX - TBC Lockwood)
Greenville, (SC - Taqueria Guadalajara #3)
Fastest
Amtrak Station
Greenville Station
No tags
Houston Bus Station
1116 Woodruff Rd
No tags
Greyhound Lines, Inc. + FlixBus
Houston Bus Station
1116 Woodruff Rd
No tags
Last refresh of the prices: Today at 5:29 PM CST.
Compare 2 ways to go from Houston to Greenville
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 6 hours 40 minutes, and with fares starting at just $165, it presents an excellent value for a comfortable ride.
Based on 87415 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $165
Based on 158 reviews, the company was rated 3.1 stars on Busbud. Travellers were especially satisfied with the power outlets and the temperature but often complained with the timeliness. Tornado Bus ticket prices on this trip start at $309
Based on 5624 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $598
Based on 11522 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $143
Based on 34 reviews, the company was rated 3 stars on Busbud. Travellers were especially satisfied with the departure location and the staff but often complained with the WiFi. Valley Transit ticket prices on this trip start at $155
Frequently asked questions about travelling from Houston, US to Greenville, SC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Houston to Greenville?
The cheapest bus tickets from Houston to Greenville start from $165. The average price for this route is around $233. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Houston to Greenville?
The average bus travel time from Houston to Greenville is 1d 6h, covering a distance of 1351 km. The quickest bus can get you there in 15h 11m and is operated by Tornado Bus.
Which bus companies service the Houston to Greenville route?
What are the earliest and latest departure times for the bus from Houston to Greenville?
The earliest bus departs from Houston to Greenville at 5:00am. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Houston to Greenville?
A bus trip from Houston to Greenville generates an estimated 34 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Houston to Greenville?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from Houston to Greenville?
Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Houston to Greenville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Houston to Greenville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12-02
$212
12-03
$262
Today
$193
12-05
$254
12-06
$204
12-07
$197
12-08
$187
12-09
$187
The cheapest trip from Houston, US to Greenville, SC was searched and found on Dec 8, 2025 with a price of $187
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Greenville, SC, as early as possible.
You can expect to pay from $187 to $3,253 for a bus ticket from Houston, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $187 which is on 2025-12-08.
Usually Tornado Bus, Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Houston, US to Greenville, SC?
The bus is the cheapest travel choice for this destination
The cheapest trip from Houston, US to Greenville, SC was searched and found on Dec 8, 2025 with a price of $187
The bus is the cheapest travel choice for this destination
